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[新冠疫情期间的消毒剂:一项挑战]

[Disinfectants during the COVID-19 pandemic: a challenge].

作者信息

Eggers Maren, Baumann Anna, Lilienthal Nils, Steinmann Eike, Steinmann Jochen, Hübner Nils-Olaf, Rabenau Holger F, Weinheimer Viola, Schwebke Ingeborg

机构信息

Kommission für Virusdesinfektion, Deutsche Vereinigung zur Bekämpfung der Viruskrankheiten (DVV) e. V., Geschäftsstelle Kiel, Kiel, Deutschland.

Gesellschaft für Virologie (GfV) e. V., Geschäftsstelle Heidelberg, Heidelberg, Deutschland.

出版信息

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2022 Jan;65(1):86-95. doi: 10.1007/s00103-021-03457-z. Epub 2021 Dec 8.

DOI:10.1007/s00103-021-03457-z
PMID:34878564
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8652094/
Abstract

Disinfection measures have become more important as a result of the COVID-19 pandemic in Germany. The increased need for disinfectants at the beginning of the pandemic required temporary legal regulations in order to provide a sufficient quantity of products for the necessary disinfection in the medical sector on the one hand and for the additional demand in the population on the other. For this purpose, the Federal Institute for Drugs and Medical Devices (BfArM) and the Federal Institute for Occupational Safety and Health (BAuA) issued a general ruling, which is explained in more detail in this article. The focus was on measures for hygienic hand disinfection. However, other applications such as surface disinfection in relation to pandemic respiratory diseases are also addressed. The experience gained in ensuring the supply of disinfectants that are effective and safe to use should be used to prepare for further pandemics.

摘要

由于德国的新冠疫情,消毒措施变得更加重要。疫情初期对消毒剂需求的增加,需要临时法律法规,以便一方面为医疗部门必要的消毒提供足够数量的产品,另一方面满足民众的额外需求。为此,联邦药品和医疗器械研究所(BfArM)和联邦职业安全与健康研究所(BAuA)发布了一项一般裁决,本文将对此进行更详细的解释。重点是卫生手消毒措施。然而,也涉及到与大流行性呼吸道疾病相关的其他应用,如表面消毒。在确保供应有效且安全使用的消毒剂方面所获得的经验,应用于为未来的大流行做准备。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/581b056927fb/103_2021_3457_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/0bd8a7611f73/103_2021_3457_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/46228c89396d/103_2021_3457_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/581b056927fb/103_2021_3457_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/0bd8a7611f73/103_2021_3457_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/46228c89396d/103_2021_3457_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/98f9/8732837/581b056927fb/103_2021_3457_Fig3_HTML.jpg

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本文引用的文献

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J Hosp Infect. 2021 Jun;112:27-30. doi: 10.1016/j.jhin.2021.03.015. Epub 2021 Mar 23.
2
Persistence of Pathogens on Inanimate Surfaces: A Narrative Review.病原体在无生命物体表面的持久性:一篇综述
Microorganisms. 2021 Feb 9;9(2):343. doi: 10.3390/microorganisms9020343.
3
The European tiered approach for virucidal efficacy testing - rationale for rapidly selecting disinfectants against emerging and re-emerging viral diseases.
欧洲针对杀病毒效力测试的分层方法——针对新发和再现病毒性疾病快速选择消毒剂的原理。
Euro Surveill. 2021 Jan;26(3). doi: 10.2807/1560-7917.ES.2021.26.3.2000708.
4
Ct values and infectivity of SARS-CoV-2 on surfaces.新型冠状病毒在物体表面的Ct值与传染性
Lancet Infect Dis. 2021 Jun;21(6):e141. doi: 10.1016/S1473-3099(20)30883-5. Epub 2020 Nov 19.
5
Ethanol is indispensable and safe as a biocidal active substance for hand disinfection.乙醇作为手部消毒的杀菌活性物质是必不可少且安全的。
J Hosp Infect. 2021 Feb;108:205-206. doi: 10.1016/j.jhin.2020.11.013. Epub 2020 Nov 18.
6
Author Correction: Aerosol and surface contamination of SARS-CoV-2 observed in quarantine and isolation care.作者更正:在隔离和检疫护理中观察到的严重急性呼吸综合征冠状病毒2的气溶胶和表面污染
Sci Rep. 2020 Aug 12;10(1):13892. doi: 10.1038/s41598-020-70939-6.
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Potential methanol toxicity and the importance of using a standardised alcohol-based hand rub formulation in the era of COVID-19.潜在的甲醇毒性以及在 COVID-19 时代使用标准化酒精基手部消毒剂配方的重要性。
Antimicrob Resist Infect Control. 2020 Aug 8;9(1):129. doi: 10.1186/s13756-020-00788-5.
8
Investigating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Surface and Air Contamination in an Acute Healthcare Setting During the Peak of the Coronavirus Disease 2019 (COVID-19) Pandemic in London.调查 2019 年冠状病毒病(COVID-19)大流行期间伦敦一家急性医疗机构内严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)的表面和空气污染情况。
Clin Infect Dis. 2021 Oct 5;73(7):e1870-e1877. doi: 10.1093/cid/ciaa905.
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Presence of SARS-CoV-2 RNA in isolation ward environment 28 days after exposure.隔离病房环境中 SARS-CoV-2 RNA 在暴露后 28 天的存在。
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Temperature-dependent surface stability of SARS-CoV-2.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的温度依赖性表面稳定性
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