Avian Influenza Research & Diagnostic Division, Animal and Plant Quarantine Agency, Gimcheon 39660, Korea.
College of Veterinary Medicine, Seoul National University, Seoul 08826, Korea.
J Vet Sci. 2021 Mar;22(2):e21. doi: 10.4142/jvs.2021.22.e21.
In this study, we describe the isolation and characterization of previously unreported Y280-lineage H9N2 viruses from two live bird markets in Korea in June 2020. Genetic analysis revealed that they were distinct from previous H9N2 viruses circulating in Korea and had highest homology to A/chicken/Shandong/1844/2019(H9N2) viruses. Their genetic constellation showed they belonged to genotype S, which is the predominant genotype in China since 2010, where genotype S viruses have infected humans and acted as internal gene donors to H5 and H7 zoonotic influenza viruses. Active surveillance and control measures need to be enhanced to protect the poultry industry and public health.
在这项研究中，我们描述了 2020 年 6 月从韩国的两个活禽市场分离并鉴定出以前未报告的 Y280 谱系 H9N2 病毒。遗传分析表明，它们与之前在韩国流行的 H9N2 病毒不同，与 A/chicken/Shandong/1844/2019(H9N2)病毒的同源性最高。它们的基因组成表明它们属于基因型 S，这是 2010 年以来中国主要的基因型，基因型 S 病毒已感染人类，并作为 H5 和 H7 人畜共患流感病毒的内部基因供体。需要加强主动监测和控制措施，以保护家禽业和公共卫生。
