Department of Prosthodontics, Faculty of Dentistry, Cukurova University, Adana, Turkey.
Fatma Kemal Timucin Dental Health Hospital, Ministry of Health, Adana, Turkey.
J Appl Biomater Funct Mater. 2021 Jan-Dec;19:2280800021989706. doi: 10.1177/2280800021989706.
The aim of this study was to investigate the surface microhardness and roughness properties of a modified glass ionomer cement formed by adding different ratios of Chitosan, when exposed to saliva and acid erosive gastric acid cycle environments.
Chitosan was added to conventional glass ionomer liquid at volumes of 5% and 10%. The chitosan-modified glass ionomer was used for the experimental group, and traditional glass ionomer formed the control group. All the groups were separated into two subgroups. One of these subgroups was subjected to a gastric acid erosive cycle. The other subgroup was immersed in artificial saliva. Microhardness, surface roughness with optical profilometer and AFM measurements of all the samples were taken. Qualitative surface topographic evaluations were made using a SEM. The data were analyzed by Kruskal-Wallis and Mann Whitney -test for pairwise comparisons of the groups at the 0.05 level of significance.
The addition of chitosan to GIC had a positive effect on the microhardness values. The gastric acid erosive cycle application negatively affected the microhardness and surface roughness properties of the sample groups.
The chitosan-modified glass ionomer cement samples showed clinically acceptable surface roughness values. Although the results of the addition of the biopolymer, chitosan, to GIC are promising, there is a need for further in-vivo studies.
本研究旨在探讨在唾液和酸侵蚀性胃酸循环环境下，添加不同比例壳聚糖的改良玻璃离子水门汀的表面显微硬度和粗糙度特性。
将壳聚糖加入到常规玻璃离子液体中，体积分别为 5%和 10%。壳聚糖改性玻璃离子水门汀为实验组，传统玻璃离子水门汀为对照组。所有组均分为两组。其中一组进行胃酸侵蚀循环，另一组浸泡在人工唾液中。对所有样本进行显微硬度、光学轮廓仪和原子力显微镜表面粗糙度测量。使用 SEM 对定性表面形貌进行评估。对各组数据进行 Kruskal-Wallis 和 Mann-Whitney U 检验，以 0.05 水平的显著性进行组间比较。
壳聚糖的添加对 GIC 的显微硬度值有积极影响。胃酸侵蚀循环应用对样品组的显微硬度和表面粗糙度特性产生负面影响。
壳聚糖改性玻璃离子水门汀样本显示出可接受的临床表面粗糙度值。尽管将生物聚合物壳聚糖添加到 GIC 中的结果很有前景，但仍需要进一步的体内研究。
