Young Ashlyn T, Pozdin Vladimir A, Daniele Michael
Joint Department of Biomedical Engineering, NC State University and UNC at Chapel Hill, Raleigh, NC, USA.
Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA.
Proc IEEE Sens. 2020 Oct;2020. doi: 10.1109/sensors47125.2020.9278636. Epub 2020 Dec 9.
Herein, a 60-electrode array is fabricated down the length of a microchamber for analysis of a microphysiological system. The electrode array is fabricated by standard photolithographic, metallization, and etching techniques. Permutations of 2-wire impedance measurements (10 Hz to 1 MHz) are made along the length of the microchannel using a multiplexer, Gamry potentiostat, and custom Labview code. An impedance "heat map" is created via custom algorithms. Spatial resolution and mapping capabilities are exhibited using conductive NaCl solutions and 2D cell culture.
在此，沿微腔长度制作了一个60电极阵列，用于微生理系统分析。电极阵列通过标准光刻、金属化和蚀刻技术制造。使用多路复用器、Gamry恒电位仪和定制的Labview代码，沿微通道长度进行2线阻抗测量（10 Hz至1 MHz）的排列。通过定制算法创建阻抗“热图”。使用导电NaCl溶液和二维细胞培养展示了空间分辨率和映射能力。
