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颗粒物对哮喘相关儿科急诊科就诊率的特定来源贡献。

Source-specific contributions of particulate matter to asthma-related pediatric emergency department utilization.

作者信息

Bhuiyan Mohammad Alfrad Nobel, Ryan Patrick, Oroumyeh Farzan, Jathan Yajna, Roy Madhumitaa, Balachandran Siv, Brokamp Cole

机构信息

Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH 45229 USA.

Department of Environmental Health, Division of Biostatistics, University of Cincinnati, Cincinnati, OH 45267 USA.

出版信息

Health Inf Sci Syst. 2021 Mar 10;9(1):12. doi: 10.1007/s13755-021-00141-z. eCollection 2021 Dec.

Abstract

UNLABELLED

Ambient particulate matter smaller than 2.5 μm (PM) is associated with different chronic diseases. It is crucial to identify the sources of ambient particulate matter to reduce the impact on health. Still, only a few studies have been linked with specific ambient particulate matter sources. In this study, we estimated the contributions of sources of PM and examined their association with daily asthma hospital utilization in Cincinnati, Ohio, USA. We used a model-based clustering method to group days with similar source-specific contributions into six distinct clusters. Specifically, elevated PM concentrations occurring on days characterized by low coal combustion contributions showed a significantly reduced risk of hospital utilization for asthma (rate ratio: 0.86, 95% CI: [0.77, 0.95]) compared to other clusters. Reducing coal combustion contribution to PM levels could be an effective intervention for lowering asthma-related hospital utilization.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s13755-021-00141-z.

摘要

未标注

小于2.5微米的环境颗粒物(PM)与不同的慢性疾病有关。识别环境颗粒物的来源对于减少其对健康的影响至关重要。然而,仅有少数研究将特定的环境颗粒物来源与之联系起来。在本研究中,我们估算了PM来源的贡献,并在美国俄亥俄州辛辛那提市研究了它们与每日哮喘住院率的关联。我们使用基于模型的聚类方法,将具有相似来源特定贡献的日子分为六个不同的类别。具体而言,与其他类别相比,在煤炭燃烧贡献较低的日子里出现的PM浓度升高,显示出哮喘住院率显著降低(率比:0.86,95%置信区间:[0.77, 0.95])。减少煤炭燃烧对PM水平的贡献可能是降低哮喘相关住院率的有效干预措施。

补充信息

在线版本包含可在10.1007/s13755-021-00141-z获取的补充材料。

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