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带血管神经移植与不带血管神经移植的实验比较

Experimental comparison of vascularized and nonvascularized nerve grafting.

作者信息

Shibata M, Tsai T M, Firrell J, Breidenbach W C

机构信息

Christine M. Kleinert Institute for Hand and Micro Surgery, Louisville, Ky.

出版信息

J Hand Surg Am. 1988 May;13(3):358-65. doi: 10.1016/s0363-5023(88)80008-x.

DOI:10.1016/s0363-5023(88)80008-x
PMID:3379269
Abstract

Previous studies have established the superiority of a vascularized nerve graft (VNG) over a nonvascularized nerve graft in a scarred recipient bed. This study compared the functional results of VNGs with nonvacularized nerve grafts (conventional nerve graft [CNG]) in a normal recipient bed. Forty rabbits were divided into two groups of 20 each. In one group a median nerve VNG was created in one forelimb. In the other group a CNG was created. Postoperative evaluation was performed at 10 and 24 weeks. Nerve conduction velocity, compound action potential area, axon diameter, and muscle weight did not demonstrate statistically significant differences. Axon counts and muscle strength did show a superior value for VNGs at 24 weeks.

摘要

先前的研究已经证实,在瘢痕化的受体床中,血管化神经移植(VNG)优于非血管化神经移植。本研究比较了在正常受体床中VNG与非血管化神经移植(传统神经移植[CNG])的功能结果。40只兔子被分为两组,每组20只。一组在一个前肢制作正中神经VNG。另一组制作CNG。在术后10周和24周进行评估。神经传导速度、复合动作电位面积、轴突直径和肌肉重量均未显示出统计学上的显著差异。在24周时,轴突计数和肌肉力量方面,VNG确实显示出更优的值。

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1
Experimental comparison of vascularized and nonvascularized nerve grafting.带血管神经移植与不带血管神经移植的实验比较
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Animal models of vascularized nerve grafts: a systematic review.血管化神经移植的动物模型:一项系统综述
Neural Regen Res. 2023 Dec;18(12):2615-2618. doi: 10.4103/1673-5374.358604.
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Nerve recovery from treatment with a vascularized nerve graft compared to an autologous non-vascularized nerve graft in animal models: A systematic review and meta-analysis.
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PLoS One. 2021 Dec 2;16(12):e0252250. doi: 10.1371/journal.pone.0252250. eCollection 2021.
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Neural Regen Res. 2020 Sep;15(9):1573-1579. doi: 10.4103/1673-5374.276327.
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Anat Rec (Hoboken). 2018 Oct;301(10):1657-1667. doi: 10.1002/ar.23919. Epub 2018 Oct 17.
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A Preliminary Assessment of the Utility of Large-Caliber Processed Nerve Allografts for the Repair of Upper Extremity Nerve Injuries.大口径处理神经同种异体移植物修复上肢神经损伤效用的初步评估
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