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[科纳克里Donka大学医院流行病与感染预防治疗中心(CTEIP)的冠状病毒病(COVID-19)儿童的流行病学和临床特征]

[Epidemiological and clinical profile of children with Coronavirus disease (COVID-19) at the Center for the Treatment of Epidemics and Infection Prevention (CTEIP) of the University Hospital of Donka in Conakry].

作者信息

Camara Emmanuel, Barry Ibrahima Koolo, Diallo Fatoumata Binta, Diallo Mohamed Lamine, Diop Mamadou Moustapha, Cherif Mahamoud Sama, Diallo Ibrahima Sory, Kouyaté Moustapha, Bangoura Mmah Aminata, Barry Aissata, Barry Mamadou Ciré, Ngadande Ipolithe Honde, Kaba Oumar, Kolié Ouo Ouo, Camara Diarra Doura, Diallo Saliou Bella, Dia Hasmiou

机构信息

Service de Pédiatrie, Hôpital National Donka, Conakry, Guinée.

Institut de Nutrition et de Santé de l´Enfant, Conakry, Guinée.

出版信息

Pan Afr Med J. 2020 Dec 21;37:363. doi: 10.11604/pamj.2020.37.363.26211. eCollection 2020.

DOI:10.11604/pamj.2020.37.363.26211
PMID:33796176
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7992426/
Abstract

COVID-19 is caused by SARS-CoV-2 virus, which is genetically similar to severe acute respiratory syndrome (SARS) virus. In pediatrics, it has a benign clinical course. Since the outbreak of COVID-19 pandemic in Guinea, whose epicenter was Conakry, pediatric cases have been reported at the CTEIP in Donka. The purpose of this study was to determine their epidemiological profile. We conducted a descriptive cross-sectional study of children aged 0-16 years admitted to the CTEIP, Donka, over a period of four months. Out of 7308 patients, coming predominantly from 5 communes of Conakry and hospitalized in the CTEPI, 189 were aged between 0 and 16 years (2 .59%). The majority of patients were within the age-group 0-4-years (38.62%) with a sex-ratio (F/M) of 1.52; 62.96% were students, 70% of children lived in Conakry, 28.57% of mothers were traders and contact persons (39.68%); 37.57% of fathers were civil servants, 2.65% of children had a history of sickle cell disease and 1.59% had allergic rhinitis. Asymptomatic patients accounted for 52.38% of cases and diagnosed patients were 74.6%. Symptoms included fever, rhinorrhea, headache, cough, abdominal pain, sneezing, diarrhea, physical asthenia. The incidence of COVID-19 among children hospitalized in the CTEIP of Donka is low. Children aged 5 years and older are more affected and nearly 50% are asymptomatic. Common symptoms are fever, headache, rhinorrhea, cough, abdominal pain, sneezing, diarrhea, physical asthenia.

摘要

新型冠状病毒肺炎(COVID-19)由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起,该病毒在基因上与严重急性呼吸综合征(SARS)病毒相似。在儿科中,其临床病程呈良性。自COVID-19疫情在几内亚爆发以来(疫情中心为科纳克里),东卡的几内亚国立教学医院儿科感染预防与控制中心(CTEIP)已报告了儿科病例。本研究的目的是确定这些病例的流行病学特征。我们对在四个月期间入住东卡CTEIP的0至16岁儿童进行了描述性横断面研究。在主要来自科纳克里5个社区并在CTEPI住院的7308名患者中,189名年龄在0至16岁之间(2.59%)。大多数患者年龄在0至4岁组(38.62%),性别比(女/男)为1.52;62.96%为学生,70%的儿童居住在科纳克里,28.57%的母亲为商人且是密切接触者(39.68%);37.57%的父亲为公务员,2.65%的儿童有镰状细胞病史,1.59%有过敏性鼻炎。无症状患者占病例的52.38%,确诊患者占74.6%。症状包括发热、流涕、头痛、咳嗽、腹痛、打喷嚏、腹泻、身体乏力。在东卡CTEIP住院儿童中,COVID-19的发病率较低。5岁及以上儿童受影响更大,近50%为无症状感染者。常见症状为发热、头痛、流涕、咳嗽、腹痛、打喷嚏、腹泻、身体乏力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/113f/7992426/613dc8c045f1/PAMJ-37-363-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/113f/7992426/613dc8c045f1/PAMJ-37-363-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/113f/7992426/613dc8c045f1/PAMJ-37-363-g001.jpg

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