体力活动对 2 型糖尿病患者牙周健康的影响。一项盲法、随机、对照试验。
Influence of physical activity on periodontal health in patients with type 2 diabetes mellitus. A blinded, randomized, controlled trial.
机构信息
Hannover Medical School, Hanover, Germany.
Department of Prosthetic Dentistry and Biomedical Materials Science, Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany.
出版信息
Clin Oral Investig. 2021 Nov;25(11):6101-6107. doi: 10.1007/s00784-021-03908-6. Epub 2021 Apr 1.
Abstract
OBJECTIVES
The aim was to investigate the effect of physical activity on periodontal health and HbA1c levels in patients with type 2 diabetes mellitus (T2DM) over a period of 6 months.
MATERIALS AND METHODS
Thirty-seven patients with non-insulin-dependent T2DM were included in the study. The intervention group (n=20) performed physical activity over a period of 6 months. The control group (n=17) did not receive any intervention. Baseline and final examinations included dental parameters and concentrations of glycosylated hemoglobin (HbA1c) and high-sensitivity C-reactive protein (hsCRP).
RESULTS
Physical activity showed a positive effect on periodontal health. Both the BOP (p= 0.005) and the severity of periodontitis (p= 0.001) were significantly reduced in the intervention group compared to the control group. Furthermore, HbA1c levels were reduced (p= 0.010) significantly in the intervention group while hsCRP levels significantly increased in the control group (p= 0.04).
CONCLUSIONS
Within the limitations of this randomized, controlled trial, physical activity over a period of 6 months is a health-promoting measure for patients with T2DM and improves both periodontal health and HbA1c concentrations.
摘要
目的
本研究旨在探究 6 个月的身体活动对 2 型糖尿病（T2DM）患者牙周健康和糖化血红蛋白（HbA1c）水平的影响。
材料与方法
研究纳入 37 例非胰岛素依赖型 T2DM 患者。干预组（n=20）接受为期 6 个月的身体活动，对照组（n=17）未接受任何干预。基线和终末检查包括牙周参数以及糖化血红蛋白（HbA1c）和高敏 C 反应蛋白（hsCRP）的浓度。
结果
身体活动对牙周健康有积极影响。与对照组相比，干预组的探诊出血（BOP）（p=0.005）和牙周炎严重程度（p=0.001）均显著降低。此外，干预组的 HbA1c 水平显著降低（p=0.010），而对照组的 hsCRP 水平显著升高（p=0.04）。
结论
在本随机对照试验的限制范围内，6 个月的身体活动是 T2DM 患者的一种促进健康的措施，可改善牙周健康和 HbA1c 浓度。
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