Institute of Physical and Theoretical Chemistry, University of Regensburg, D-93040 Regensburg, Germany.
Institute of Physical and Theoretical Chemistry, University of Regensburg, D-93040 Regensburg, Germany.
Food Chem. 2021 Sep 1;355:129624. doi: 10.1016/j.foodchem.2021.129624. Epub 2021 Mar 20.
A choline chloride + lactic acid (1:1) natural deep eutectic solvent (NADES) is used as an adjuvant to ethanol/triacetin mixtures to solubilize and extract curcumin from Curcuma Longa. The obtained NADES/ethanol/triacetin mixtures are homogeneous, transparent and of low viscosity even in the absence of water. Dynamic light scattering revealed significant nanostructures, typical of surfactant-free microemulsions. A twofold increase of curcumin solubility and remarkable extraction power (yield of ~90%) can be achieved in the ternary system including the NADES, although curcumin is hydrophobic and the used NADES are very polar. Due to the elevated solubility of curcumin, more extraction cycles can be made than in the previously published aqueous systems with the same amount of solution. As a result, less solvent is required to achieve the same extraction yield.
胆碱氯化物+乳酸（1:1）自然深共晶溶剂（NADES）被用作乙醇/三醋酸甘油酯混合物的助剂，以从姜黄中溶解和提取姜黄素。即使没有水，所得到的 NADES/乙醇/三醋酸甘油酯混合物也是均匀的、透明的和低粘度的。动态光散射显示出显著的纳米结构，典型的无表面活性剂微乳液。在包括 NADES 的三元体系中，可以使姜黄素的溶解度增加一倍，提取能力（收率约为 90%）显著提高，尽管姜黄素是疏水性的，而且所用的 NADES 非常极性。由于姜黄素的溶解度增加，与具有相同溶液量的先前公布的水性体系相比，可以进行更多的提取循环。因此，达到相同的提取产率所需的溶剂更少。
