Tohme Tohme, Magaud Pascale, Baldas Lucien
Institut Clément Ader (ICA), INSA, ISAE-SUPAERO, Mines-Albi, UPS, Université de Toulouse, 3 rue Caroline Aigle, 31400 Toulouse, France.
Micromachines (Basel). 2021 Mar 7;12(3):277. doi: 10.3390/mi12030277.
Understanding the behavior of a single particle flowing in a microchannel is a necessary step in designing and optimizing efficient microfluidic devices for the separation, concentration, counting, detecting, sorting, or mixing of particles in suspension. Although the inertial migration of spherical particles has been deeply investigated in the last two decades, most of the targeted applications involve shaped particles whose behavior in microflows is still far from being completely understood. While traveling in a channel, a particle both rotates and translates: it translates in the streamwise direction driven by the fluid flow but also in the cross-section perpendicular to the streamwise direction due to inertial effects. In addition, particles' rotation and translation motions are coupled. Most of the existing works investigating the transport of particles in microchannels decouple their rotational and lateral migration behaviors: particle rotation is mainly studied in simple shear flows, whereas lateral migration is neglected, and studies on lateral migration mostly focus on spherical particles whose rotational behavior is simple. The aim of this review is to provide a summary of the different works existing in the literature on the inertial migration and the rotational behavior of non-spherical particles with a focus and discussion on the remaining scientific challenges in this field.
了解单个粒子在微通道中的流动行为是设计和优化高效微流控设备的必要步骤，这些设备用于悬浮液中粒子的分离、浓缩、计数、检测、分选或混合。尽管在过去二十年中对球形粒子的惯性迁移进行了深入研究，但大多数目标应用涉及异形粒子，其在微流中的行为仍远未被完全理解。在通道中移动时，粒子既会旋转又会平移：它在流体流动驱动的流向方向上平移，同时由于惯性效应也会在垂直于流向方向的横截面上平移。此外，粒子的旋转和平移运动是相互耦合的。大多数现有研究微通道中粒子传输的工作将其旋转和横向迁移行为解耦：粒子旋转主要在简单剪切流中进行研究，而横向迁移被忽略，并且关于横向迁移的研究大多集中在旋转行为简单的球形粒子上。本综述的目的是总结文献中关于非球形粒子惯性迁移和旋转行为的不同研究工作，并重点讨论该领域中仍然存在的科学挑战。
