Laboratorio Nacional de Fusion, CIEMAT, Av Complutense 40, 28040 Madrid, Spain.
Department for Surface Engineering, Jožef Stefan Institute Jamova cesta 39, 1000 Ljubljana, Slovenia.
Molecules. 2021 Mar 28;26(7):1903. doi: 10.3390/molecules26071903.
In this paper, a review of cold plasma setups and the physical and chemical processes leading to the generation of active species is presented. The emphasis is given to the interaction of cold plasmas with materials used in medical applications, especially medical implants as well as live cells. An overview of the different kinds of plasmas and techniques used for generation of active species, which significantly alter the surface properties of biomaterials is presented. The elemental processes responsible for the observed changes in the physio-chemical properties of surfaces when exposed to plasma are described. Examples of ongoing research in the field are given to illustrate the state-of-the-art at the more conceptual level.
本文综述了冷等离子体设备以及导致活性物质生成的物理和化学过程。重点介绍了冷等离子体与医疗应用中使用的材料(特别是医疗植入物和活细胞)的相互作用。本文概述了用于产生显著改变生物材料表面特性的活性物质的不同类型等离子体和技术。描述了暴露于等离子体时表面物理化学性质发生变化的基本过程。给出了该领域正在进行的研究示例,以更具概念性的角度说明当前的研究水平。