Laboratorio de Medios e Interfases (LAMEIN), DBI, FACET, Universidad Nacional de Tucumán, Av. Independencia 1800, 4000 Tucumán, Argentina.
Instituto Superior de Investigaciones Biológicas (INSIBIO), CONICET, Chacabuco 461, 4000 Tucumán, Argentina.
Sensors (Basel). 2021 Mar 21;21(6):2204. doi: 10.3390/s21062204.
In recent years, several devices have been developed for the direct measurement of hydrogen peroxide (H2O2), a key compound in biological processes and an important chemical reagent in industrial applications. Classical enzymatic biosensors for H2O2 have been recently outclassed by electrochemical sensors that take advantage of material properties in the nano range. Electrodes with metal nanoparticles (NPs) such as Pt, Au, Pd and Ag have been widely used, often in combination with organic and inorganic molecules to improve the sensing capabilities. In this review, we present an overview of nanomaterials, molecules, polymers, and transduction methods used in the optimization of electrochemical sensors for H2O2 sensing. The different devices are compared on the basis of the sensitivity values, the limit of detection (LOD) and the linear range of application reported in the literature. The review aims to provide an overview of the advantages associated with different nanostructures to assess which one best suits a target application.
近年来，已经开发出了几种用于直接测量过氧化氢（H2O2）的设备，H2O2 是生物过程中的关键化合物，也是工业应用中的重要化学试剂。最近，电化学传感器在 H2O2 的检测方面已经超越了经典的酶生物传感器，它们利用了纳米范围内的材料特性。具有金属纳米粒子（NPs）的电极，如 Pt、Au、Pd 和 Ag 已经被广泛使用，通常与有机和无机分子结合使用，以提高传感性能。在本文中，我们综述了用于优化电化学 H2O2 传感器的纳米材料、分子、聚合物和转换方法。根据文献中报道的灵敏度值、检测限（LOD）和应用线性范围，对不同的器件进行了比较。本文综述的目的是概述与不同纳米结构相关的优点，以评估哪种结构最适合目标应用。
