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与持续输注舒芬太尼相比,使用脊髓麻醉联合肋间神经麻醉以改善单侧乳房切除术猫的镇痛效果。

Use of Spinal Anaesthesia with Anaesthetic Block of Intercostal Nerves Compared to a Continuous Infusion of Sufentanyl to Improve Analgesia in Cats Undergoing Unilateral Mastectomy.

作者信息

Cicirelli Vincenzo, Debidda Pasquale, Maggio Nicola, Caira Michele, Mrenoshki Daniela, Aiudi Giulio G, Lacalandra Giovanni M

机构信息

Department of Veterinary Medicine, University of Bari Aldo Moro, 70121 Bari, Italy.

出版信息

Animals (Basel). 2021 Mar 20;11(3):887. doi: 10.3390/ani11030887.

Abstract

Unilateral mastectomy is a common surgical procedure in feline species and requires postoperative pain management. Our study aimed to evaluate the analgesic efficacy of subarachnoid anaesthesia combined with an intercostal nerve block, in comparison with the use of sufentanyl citrate administered as a constant-rate infusion (CRI). Twenty cats were randomly divided into two groups ( = 10/group) based on the analgesic protocol used: the first received loco-regional anaesthesia with levobupivacaine (LR group), and the second received a CRI of sufentanyl (SUF group). The evaluation criteria during surgery were the need for a bolus of fentanyl in the event of an increased heart rate or increased blood pressure. In the postoperative period, the levels of comfort/discomfort and pain were used to obtain a score according to the UNESP-Botucatu multimodal scale. Subjects who scored above seven received analgesic drug supplementation. Intraoperative analgesia was satisfactory, with good haemodynamic stability in both groups. Four patients in the LR group required an extra dose of methadone after they achieved the sternal decubitus position, whereas those in the SUF group required many more doses. The analgesia achieved in the LR group was more satisfactory than that in the SUF group.

摘要

单侧乳房切除术是猫科动物常见的外科手术,术后需要进行疼痛管理。我们的研究旨在评估蛛网膜下腔麻醉联合肋间神经阻滞的镇痛效果,并与枸橼酸舒芬太尼持续静脉输注(CRI)的效果进行比较。根据所采用的镇痛方案,将20只猫随机分为两组(每组 = 10只):第一组接受左旋布比卡因局部区域麻醉(LR组),第二组接受舒芬太尼持续静脉输注(SUF组)。手术期间的评估标准是在心率加快或血压升高时是否需要推注芬太尼。术后,根据UNESP - 博图卡图多模式量表,利用舒适/不适和疼痛程度来打分。得分高于7分的受试者接受补充镇痛药治疗。两组术中镇痛效果均令人满意,血流动力学稳定性良好。LR组有4只猫在达到仰卧位后需要额外注射一剂美沙酮,而SUF组的猫需要更多剂量。LR组的镇痛效果比SUF组更令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36fd/8003676/272b6f656e78/animals-11-00887-g001.jpg

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