Institute of Collective Health, Federal University of Bahia, R. Basílio da Gama, s/n - Canela, Salvador, 45760-030, Bahia, Brazil.
Center of Health Sciences, Universidade Federal do Recôncavo da Bahia, Bahia, Brazil.
AIDS Behav. 2024 Jul;28(7):2193-2204. doi: 10.1007/s10461-024-04351-w. Epub 2024 May 7.
This study aims to estimate the COVID-19 vaccine acceptance and hesitancy among people living with HIV (PLWHA). A search for observational studies was conducted in five databases and preprinted literature. Summary estimates were pooled using a random effects model and meta-regression. Of 150 identified studies, 31 were eligible (18,550 PLWHA). The weighted prevalence of COVID-19 vaccine hesitancy overall was 29.07% among PLWHA (95%CI = 24.33-34.32; I² = 98%,) and that of vaccine acceptance was 68.66% (95%CI = 62.25-74.43; I² = 98%). Higher hesitancy prevalence was identified in low/lower-middle income countries (35.05; 95% CI = 19.38-54.78). The heterogeneity was explained by the risk of bias, region, and year of data collection. The findings conclude that the COVID-19 vaccine hesitancy rate remains high, especially in low-income countries. Evidence-informed interventions aimed at increasing COVID-19 vaccine acceptance at the national and individual levels ought to be designed to increase COVID-19 vaccine acceptance among PLWHA.
本研究旨在评估 HIV 感染者（PLWHA）对 COVID-19 疫苗的接受度和犹豫情况。在五个数据库和预印本文献中进行了观察性研究的检索。使用随机效应模型和荟萃回归对汇总估计值进行了汇总。在确定的 150 项研究中，有 31 项符合条件（18,550 名 PLWHA）。PLWHA 中 COVID-19 疫苗犹豫的加权总体患病率为 29.07%（95%CI=24.33-34.32；I²=98%），疫苗接受率为 68.66%（95%CI=62.25-74.43；I²=98%）。在中低收入国家，疫苗犹豫的患病率更高（35.05%；95%CI=19.38-54.78）。异质性可通过偏倚风险、区域和数据收集年份来解释。研究结果表明，COVID-19 疫苗犹豫率仍然很高，尤其是在低收入国家。应该在国家和个人层面设计以证据为基础的干预措施，以提高 PLWHA 对 COVID-19 疫苗的接受度。
