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用于食品、饲料和水中小分子安全性和真实性常规分析的高分辨率质谱法适用性综述

Suitability of High-Resolution Mass Spectrometry for Routine Analysis of Small Molecules in Food, Feed and Water for Safety and Authenticity Purposes: A Review.

作者信息

Gavage Maxime, Delahaut Philippe, Gillard Nathalie

机构信息

CER Groupe, Rue du Point du Jour 8, 6900 Marloie, Belgium.

出版信息

Foods. 2021 Mar 12;10(3):601. doi: 10.3390/foods10030601.

DOI:10.3390/foods10030601
PMID:33809149
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7998992/
Abstract

During the last decade, food, feed and environmental analysis using high-resolution mass spectrometry became increasingly popular. Recent accessibility and technological improvements of this system make it a potential tool for routine laboratory work. However, this kind of instrument is still often considered a research tool. The wide range of potential contaminants and residues that must be monitored, including pesticides, veterinary drugs and natural toxins, is steadily increasing. Thanks to full-scan analysis and the theoretically unlimited number of compounds that can be screened in a single analysis, high-resolution mass spectrometry is particularly well-suited for food, feed and water analysis. This review aims, through a series of relevant selected studies and developed methods dedicated to the different classes of contaminants and residues, to demonstrate that high-resolution mass spectrometry can reach detection levels in compliance with current legislation and is a versatile and appropriate tool for routine testing.

摘要

在过去十年中,使用高分辨率质谱法进行食品、饲料和环境分析越来越普遍。该系统近期的可及性和技术改进使其成为常规实验室工作的潜在工具。然而,这类仪器仍常被视为研究工具。必须监测的潜在污染物和残留物种类繁多,包括农药、兽药和天然毒素,且数量在不断增加。得益于全扫描分析以及单次分析中理论上可筛查的化合物数量不受限制,高分辨率质谱法特别适用于食品、饲料和水的分析。本综述旨在通过一系列相关的选定研究以及针对不同类别污染物和残留物开发的方法,证明高分辨率质谱法能够达到符合现行法规的检测水平,并且是用于常规检测的通用且合适的工具。

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