Michalek-Zrabkowska Monika, Wieckiewicz Mieszko, Gac Pawel, Smardz Joanna, Poreba Rafal, Wojakowska Anna, Goslawska Katarzyna, Mazur Grzegorz, Martynowicz Helena
Department of Internal Medicine, Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, 213 Borowska St., 50-556 Wroclaw, Poland.
Department of Experimental Dentistry, Wroclaw Medical University, 26 Krakowska St., 50-425 Wroclaw, Poland.
J Clin Med. 2021 Mar 22;10(6):1304. doi: 10.3390/jcm10061304.
The present research aimed to investigate the influence of sleep bruxism (SB) intensity on blood pressure parameters in normotensive subjects by using an ambulatory blood pressure device. The study group included 65 normotensive individuals suspected of having SB. All participants underwent one-night video-polysomnography, and ambulatory blood pressure monitoring was performed the next day; 86.15% of them were diagnosed with SB. Statistical analysis included correlation and regression analysis. The obtained results showed that systolic blood pressure variability during sleep significantly increased in individuals with BEI > 4 (bruxism episodes index; episodes/hour) compared to those with BEI ≤ 4 (8.81 ± 3.36 versus 10.57 ± 3.39, = 0.05). Multivariable regression analysis showed that systolic blood pressure variability at nighttime was also associated with the following independent risk factors: higher apnea-to-bruxism index, male gender, BEI > 4 episodes/hour, body mass index (BMI) ≥ 25 kg/m, higher arousal index, and shorter total sleep time. In summary, sleep bruxism intensity was associated with increased systolic blood pressure variability during sleep. Coincidental apnea, male gender, severe sleep bruxism (SB intensity with BEI > 4/hour), excess weight and obesity, higher arousal index, and shorter sleep time seem to be the main determinants that influence blood pressure in normotensive sleep bruxers.
本研究旨在通过使用动态血压监测设备，调查睡眠磨牙症（SB）强度对血压正常受试者血压参数的影响。研究组包括65名疑似患有SB的血压正常个体。所有参与者均接受了一晚的视频多导睡眠图监测，并于次日进行了动态血压监测；其中86.15%被诊断为患有SB。统计分析包括相关性和回归分析。结果显示，与BEI≤4的个体相比，BEI>4（磨牙症发作指数；发作次数/小时）的个体睡眠期间收缩压变异性显著增加（8.81±3.36对10.57±3.39，P=0.05）。多变量回归分析显示，夜间收缩压变异性还与以下独立危险因素相关：较高的呼吸暂停与磨牙症指数、男性、BEI>4次/小时、体重指数（BMI）≥25kg/m²、较高的觉醒指数和较短的总睡眠时间。总之，睡眠磨牙症强度与睡眠期间收缩压变异性增加有关。同时出现的呼吸暂停、男性、严重睡眠磨牙症（SB强度为BEI>4/小时）、超重和肥胖、较高的觉醒指数以及较短的睡眠时间似乎是影响血压正常的睡眠磨牙症患者血压的主要决定因素。
