梅毒各阶段的免疫反应模式。
The pattern of immunological responses at various stages of syphilis.
作者信息
Shannon R, Booth S D
出版信息
Br J Vener Dis. 1977 Oct;53(5):281-6. doi: 10.1136/sti.53.5.281.
Abstract
Each of 212 sera, taken from 129 patients with clinically established syphilis, was subjected to seven immunological tests. The tests were designed to detect both anti-lipoidal and anti-treponemal antibodies and to titrate antibody of both IgG and IgM molecular species. It was found that patients of similar clinical history were usually recognisable by the similarity of results obtained in the seven tests, and a progression of these patterns of results was also found in samples of serum taken from individual patients during the course of their disease. It is suggested that this more comprehensive type of serological examination of patients can provide valuable information to the clinician.
摘要
从129例临床确诊梅毒患者身上采集的212份血清样本，每份都接受了7项免疫学检测。这些检测旨在同时检测抗类脂质抗体和抗梅毒螺旋体抗体，并对IgG和IgM两种分子类型的抗体进行滴定。研究发现，具有相似临床病史的患者，通常可以通过这7项检测结果的相似性来识别，而且在个体患者病程中采集的血清样本中，这些检测结果模式也呈现出一种变化趋势。研究表明，这种对患者更全面的血清学检查可为临床医生提供有价值的信息。
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