Savolainen Lauri, Timpmann Saima, Mooses Martin, Mäestu Evelin, Medijainen Luule, Tõnutare Lisette, Ross Frederik, Lellsaar Märt, Unt Eve, Ööpik Vahur
Institute of Sport Sciences and Physiotherapy, University of Tartu, 18 Ülikooli St, 50090, Tartu, Estonia.
Department of Cardiology, Institute of Clinical Medicine, University of Tartu, Tartu, Estonia.
Eur J Appl Physiol. 2021 Jul;121(7):2077-2090. doi: 10.1007/s00421-021-04674-9. Epub 2021 Apr 5.
Vitamin D (Vit-D) supplementation has been shown to increased muscle strength in young adults. It remains unclear if Vit-D supplementation enhances the efficacy of resistance training (RT). This study tested the hypothesis that Vit-D supplementation would enhance the RT-induced increases in muscle strength and lean body mass (LBM) in Vit-D deficient young men.
Thirty-nine men (baseline serum 25(OH)D < 50 nmol L) were quasi-randomly assigned to one of the two groups that performed a 12-week supervised RT program concomitant with either Vit-D (8000 IU daily; VD) or placebo (PLC) supplementation.
During 12-week RT, energy and nutrient (except Vit-D) intake and training loads did not differ in the two groups. Serum 25(OH)D levels increased from 36.3 ± 9.2 to 142.4 ± 21.9 nmol L (P < 0.05) in VD group and remained unchanged between 36.3 ± 8.9 and 29.4 ± 6.6 nmol L (P > 0.05) in PLC group. Muscle strength (1-repetition maximum) increased (P < 0.05) to an equal extent in the two groups in 5 exercises performed on RT equipment, whereas strength gains in chest press and seated row were greater (P < 0.05) in PLC compared to VD group. Total and regional LBM (measured by DXA scan) increased (P < 0.05) equally in the two groups. Android fat mass decreased (P < 0.05) in VD group only.
Vit-D supplementation does not enhance the efficacy of RT in terms of muscle strength and LBM gains in Vit-D deficient young healthy men.
维生素D（Vit-D）补充剂已被证明可增强年轻人的肌肉力量。Vit-D补充剂是否能提高抗阻训练（RT）的效果仍不清楚。本研究检验了以下假设：补充Vit-D可增强RT诱导的维生素D缺乏年轻男性肌肉力量和瘦体重（LBM）的增加。
39名男性（基线血清25(OH)D＜50 nmol/L）被准随机分配到两组中的一组，这两组都进行了为期12周的有监督的RT计划，同时分别补充Vit-D（每日8000 IU；VD）或安慰剂（PLC）。
在为期12周的RT期间，两组的能量和营养素（维生素D除外）摄入量以及训练负荷没有差异。VD组血清25(OH)D水平从36.3±9.2 nmol/L增加到142.4±21.9 nmol/L（P＜0.05），而PLC组在36.3±8.9 nmol/L和29.4±6.6 nmol/L之间保持不变（P＞0.05）。在RT设备上进行的5项运动中，两组的肌肉力量（1次重复最大值）增加程度相同（P＜0.05），而与VD组相比，PLC组在卧推和坐姿划船中的力量增加更大（P＜0.05）。两组的全身和局部LBM（通过双能X线吸收法扫描测量）增加程度相同（P＜0.05）。仅VD组的腹部脂肪量减少（P＜0.05）。
在维生素D缺乏的年轻健康男性中，补充Vit-D在增加肌肉力量和LBM方面并不能提高RT的效果。
