Department of Nutrition, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mother Infant Research Institute, Tufts Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA.
Clin Obes. 2021 Aug;11(4):e12455. doi: 10.1111/cob.12455. Epub 2021 Apr 9.
Test the hypothesis that women with obesity have greater gestation weight gain (GWG) with a moderately higher, vs lower, carbohydrate (CHO) diet, independent of energy intake, whereas GWG for women of normal weight would not differ by CHO group. This was a secondary analysis of data collected from glucose tolerant women with normal weight (NW) or obesity in pregnancy. Women completed a three-day food diary 16 to 20 weeks. A median split for percent kilocalories from CHO (median = 49.6%) categorized women into moderately highCHO vs lowCHO groups (n = 13-15/group). GWG was calculated between consent and the last prenatal care visit. A two-way ANOVA was used to examine whether there was an interaction between weight status and CHO group on GWG, independent of energy intake, time between consent and last prenatal visit, and age. Women in both highCHO groups consumed more sugars and starches compared to women in the lowCHO groups (P < .05). A significant interaction between weight status and CHO content of the diet was found (P < .05), such that, for women with obesity, those consuming a lowCHO diet had less GWG than those consuming a highCHO diet, whereas the pattern was opposite for women with NW. Results suggest that intake of a moderately lower CHO diet may help limit GWG among glucose tolerant women with obesity. Given that women in this study were eligible only if they had normal fasting glucose concentrations in early pregnancy, it is not clear if these results would generalize to all women with obesity during pregnancy.
与较低碳水化合物(CHO)饮食相比,肥胖女性的妊娠增重(GWG)会有适度增加,而体重正常的女性的 GWG 则不会因 CHO 组而异。这是对妊娠期间体重正常(NW)或肥胖的糖耐量正常女性收集的数据进行的二次分析。女性在 16 至 20 周时完成了三天的食物日记。CHO 卡路里百分比的中位数分割(中位数=49.6%)将女性分为高 CHO 和低 CHO 组(每组 13-15 人)。GWG 是在同意和最后一次产前检查之间计算的。采用双向方差分析检查 GWG 与体重状况和 CHO 组之间是否存在独立于能量摄入、同意和最后一次产前检查之间的时间以及年龄的相互作用。与低 CHO 组相比,高 CHO 组的女性消耗更多的糖和淀粉(P<0.05)。发现体重状况和饮食 CHO 含量之间存在显著的相互作用(P<0.05),即对于肥胖女性,摄入低 CHO 饮食的女性 GWG 少于摄入高 CHO 饮食的女性,而 NW 女性的模式则相反。结果表明,摄入中等较低的 CHO 饮食可能有助于限制糖耐量正常的肥胖女性的 GWG。鉴于本研究中的女性只有在妊娠早期空腹血糖正常才有资格参加,因此尚不清楚这些结果是否适用于所有肥胖孕妇。