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使用 BokaFloTM 器械测量唾液流量。

The use of BokaFlo™ instrument to measure salivary flow.

机构信息

School of Dentistry, University of Utah, Salt Lake City, UT, USA.

出版信息

BMC Oral Health. 2021 Apr 12;21(1):191. doi: 10.1186/s12903-021-01477-4.

Abstract

BACKGROUND

Dry mouth currently affects roughly 20% of the population and is a condition characterized by chronic hyposalivation and/or subjective reports of xerostomia. Low saliva flow can be indicative of other undiagnosed diseases, such as primary Sjogren's syndrome, and may contribute to difficulty chewing, increased caries susceptibility and infection. The passive drool test (PDT) is the primary method used to evaluate patients for hyposalivation but it is time-consuming and inconvenient. New methodology is needed to facilitate increased testing for hyposalivation in the dental clinic. The aim of this study was to evaluate an alternative method to measure salivary flow in dental offices.

METHODS

In this study, we tested a new biomedical device, the BokaFlo™, to measure salivary flow in subjects in comparison to the current PDT standard. Participants completed an oral health questionnaire and saliva flow was evaluated by the PDT and the BokaFlo™ system.

RESULTS

Saliva flow as measured by the BokaFlo™ positively correlated with the saliva flow measured by the PDT methodology (r = 0.22, p < 0.05). The device predicted low saliva flow in subjects with a sensitivity of 0.76 and specificity of 0.84 for subjects with hyposalivation, defined as a saliva flow rate of ≤ 0.1 ml/min. A significant negative correlation between the total oral health questionnaire score and the likelihood of participant exhibiting low salivary flow was observed (r = - 0.31, p < 0.006).

CONCLUSION

The BokaFlo™ was effectively able to measure low saliva flow correlating with the PDT methodology and may provide more efficient testing of saliva flow in the dental office.

摘要

背景

目前大约有 20%的人口患有口干症,其特征是慢性唾液分泌减少和/或主观的口干报告。低唾液流量可能表明存在其他未确诊的疾病,如原发性干燥综合征,并可能导致咀嚼困难、龋齿易感性增加和感染。被动流涎试验(PDT)是评估患者唾液分泌减少的主要方法,但它既耗时又不方便。需要新的方法学来促进在牙科诊所中增加唾液分泌减少的测试。本研究的目的是评估一种替代方法来测量牙科诊所中的唾液流量。

方法

在这项研究中,我们测试了一种新的生物医学设备,即 BokaFlo™,以比较当前 PDT 标准来测量受试者的唾液流量。参与者完成了口腔健康问卷,通过 PDT 和 BokaFlo™系统评估唾液流量。

结果

BokaFlo™测量的唾液流量与 PDT 方法测量的唾液流量呈正相关(r=0.22,p<0.05)。该设备对唾液分泌减少的受试者具有较高的预测能力,其对唾液分泌减少受试者的敏感性为 0.76,特异性为 0.84,定义为唾液流速≤0.1ml/min。观察到总口腔健康问卷评分与受试者表现出低唾液流量的可能性之间存在显著负相关(r=-0.31,p<0.006)。

结论

BokaFlo™能够有效地测量低唾液流量,与 PDT 方法学相关联,并且可能在牙科诊所中提供更有效的唾液流量测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0df9/8042968/2cd66891e2f7/12903_2021_1477_Fig1_HTML.jpg

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