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嗅觉和味觉障碍:从古至今到 COVID-19。

Olfaction and anosmia: From ancient times to COVID-19.

机构信息

Department of Neurology (Nerve-Muscle Unit), University Hospital of Bordeaux (CHU Bordeaux), Pellegrin Hospital, 1 place Amélie Raba-Léon, 33076 Bordeaux, France; Grand Sud-Ouest' National Reference Center for neuromuscular disorders, University Hospital of Bordeaux (CHU Bordeaux), Pellegrin Hospital, 1 place Amélie Raba-Léon, 33076 Bordeaux, France; ALS Center, University Hospital of Bordeaux (CHU Bordeaux), Pellegrin Hospital, 1 place Amélie Raba-Léon, 33076 Bordeaux, France.

Department of Neurology (Nerve-Muscle Unit), University Hospital of Bordeaux (CHU Bordeaux), Pellegrin Hospital, 1 place Amélie Raba-Léon, 33076 Bordeaux, France; Grand Sud-Ouest' National Reference Center for neuromuscular disorders, University Hospital of Bordeaux (CHU Bordeaux), Pellegrin Hospital, 1 place Amélie Raba-Léon, 33076 Bordeaux, France; ALS Center, University Hospital of Bordeaux (CHU Bordeaux), Pellegrin Hospital, 1 place Amélie Raba-Léon, 33076 Bordeaux, France; Neurocentre François Magendie, Unité INSERM 1215, 146 Rue Léo Saignat, 33077 Bordeaux Cedex, France.

出版信息

J Neurol Sci. 2021 Jun 15;425:117433. doi: 10.1016/j.jns.2021.117433. Epub 2021 Apr 3.

Abstract

Olfaction, one of our five main qualitative sensory abilities, is the action of smelling or the capacity to smell. Olfactory impairment can be a sign of a medical problem, from a benign nasal/sinus problem up to a potentially serious brain injury. However, although clinicians (neurologists or not) usually test the olfactory nerves in specific clinical situations (for example, when a neurodegenerative disorder is suspected), they may omit such tests in many other situations. With the recent COVID-19 pandemic, the resurgence of anosmia has reminded us of the importance of testing this sensorineural function. We retrace here the main historical steps and discoveries concerning olfaction and anosmia.

摘要

嗅觉是我们五种主要的定性感觉能力之一,是指嗅觉或嗅闻的能力。嗅觉障碍可能是某种医疗问题的迹象,从良性的鼻腔/鼻窦问题到潜在的严重脑损伤都有可能。然而,尽管临床医生(神经科医生或其他医生)通常在特定的临床情况下(例如,当怀疑有神经退行性疾病时)测试嗅觉神经,但在许多其他情况下可能会省略这些测试。随着最近 COVID-19 大流行的爆发,嗅觉丧失的再次出现提醒我们测试这种感觉神经功能的重要性。我们在这里回顾了有关嗅觉和嗅觉丧失的主要历史步骤和发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ab0/9755649/7d3d10e22f8a/ga1_lrg.jpg

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