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脓毒症和感染性休克早期处理的更新与争议。

Updates and controversies in the early management of sepsis and septic shock.

机构信息

Associate Professor & Associate Chair, Clinical Operations; Medical Director, Emergency Medicine Clinical Center University of Florida – Jacksonville, Jacksonville, FL

Associate Professor of Emergency Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL

出版信息

Emerg Med Pract. 2021 Apr 15;23(Suppl 4-2):1-24.

PMID:33852263
Abstract

Sepsis is a common and life-threatening condition that requires early recognition and swift initial management. Diagnosis and treatment of sepsis and septic shock are fundamental for emergency clinicians, and include knowledge of clinical and laboratory indicators of subtle and overt organ dysfunction, infection source control, and protocols for prompt identification of the early signs of septic shock. This issue is a structured review of the literature on the management of sepsis, focusing on the current evidence, guidelines, and protocols.

摘要

脓毒症是一种常见且危及生命的病症,需要及早识别和迅速初始管理。脓毒症和感染性休克的诊断和治疗对急诊临床医生至关重要,包括了解细微和明显器官功能障碍的临床和实验室指标、感染源控制,以及迅速识别感染性休克早期迹象的方案。本问题是对脓毒症处理的文献进行的结构化综述,重点关注当前的证据、指南和方案。

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Updates and controversies in the early management of sepsis and septic shock.脓毒症和感染性休克早期处理的更新与争议。
Emerg Med Pract. 2021 Apr 15;23(Suppl 4-2):1-24.
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Updates and controversies in the early management of sepsis and septic shock.脓毒症和脓毒性休克早期管理的进展与争议
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About severe sepsis and septic shock.关于严重脓毒症和脓毒性休克。
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引用本文的文献

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Value of SOFA score, APACHE II score, and WBC count for mortality risk assessment in septic patients: A retrospective study.序贯器官衰竭评估(SOFA)评分、急性生理与慢性健康状况评分系统(APACHE)II评分及白细胞计数在脓毒症患者死亡风险评估中的价值:一项回顾性研究
Medicine (Baltimore). 2025 May 16;104(20):e42464. doi: 10.1097/MD.0000000000042464.
2
Population-specific genetic-risk scores enable improved prediction of mortality within 28 days of sepsis onset: a retrospective Taiwanese cohort study.特定人群的遗传风险评分能够改善脓毒症发作后28天内死亡率的预测:一项台湾回顾性队列研究。
J Intensive Care. 2025 Feb 26;13(1):11. doi: 10.1186/s40560-025-00783-1.
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Identification of Immune-Related Genes as Potential Biomarkers in Early Septic Shock.
免疫相关基因作为早期脓毒性休克潜在生物标志物的鉴定
Int Arch Allergy Immunol. 2025;186(3):264-279. doi: 10.1159/000540949. Epub 2024 Sep 30.
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Efficacy of immediate versus delayed renal replacement therapy in septic patients undergoing continuous renal replacement therapy.脓毒症患者接受连续性肾脏替代治疗时即时与延迟肾脏替代治疗的疗效比较
Am J Transl Res. 2024 Aug 15;16(8):3646-3653. doi: 10.62347/XSTK3213. eCollection 2024.
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The Relationship between Serum CXCL8 and ET-1 Expression Levels and Sepsis Complicated with Heart Failure.血清CXCL8与ET-1表达水平及脓毒症合并心力衰竭的关系
Cardiol Res Pract. 2022 Aug 27;2022:8570486. doi: 10.1155/2022/8570486. eCollection 2022.
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Tissue-Type Plasminogen Activator-Inhibitor Complex as an Early Predictor of Septic Shock: A Retrospective, Single-Center Study.组织型纤溶酶原激活物抑制剂复合物作为脓毒性休克的早期预测指标:一项回顾性单中心研究。
Dis Markers. 2022 Apr 4;2022:9364037. doi: 10.1155/2022/9364037. eCollection 2022.
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Sepsis Management, Controversies, and Advancement in Nanotechnology: A Systematic Review.脓毒症管理、争议与纳米技术进展:一项系统综述
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