Het Oogziekenhuis Rotterdam, Schiedamse Vest 180, 3011 BH, Rotterdam, The Netherlands.
OLVG, Amsterdam, The Netherlands.
Graefes Arch Clin Exp Ophthalmol. 2021 Jul;259(7):1897-1905. doi: 10.1007/s00417-021-05181-5. Epub 2021 Apr 14.
To evaluate in a large sample of patients from 10 different European centers the results of cataract surgery, characterizing the relationship between patient-reported outcomes (PROMs) and clinician-reported outcome measures (CROMs).
Prospective non-interventional multicenter observational descriptive study analyzing the clinical outcomes of a total of 3799 cases undergoing cataract surgery (mean age: 72.7 years). In all cases, the cataract surgery standard developed by the International Consortium for Health Outcomes Measurements (ICHOM) was used to register the clinical data. Three-month postoperative visual acuity and refraction data were considered CROMs, whereas Rasch-calibrated item 2 (RCCQ2) and total Catquest-9SF score (CQ) were considered PROMs.
Postoperative corrected distance visual acuity (CDVA) was 0.3 logMAR or better in 88.7% (2505/2823) of eyes. Mean differences between preoperative and postoperative RCCQ2 and CQ scores were -3.09 and -2.39, respectively. Visual function improvement with surgery was reported by 91.5% (2163/2364) of patients. Statistically significant, although weak, correlations of postoperative CDVA with postoperative refraction, PROMs, and complications were found (0.133 ≤ r ≤0.289, p < 0.001). A predictive model (R: 0.254) of postoperative CDVA considering 10 variables was obtained, including preoperative CDVA, different ocular comorbidities, age, gender and intraoperative complications. Likewise, another predictive model (R: 0.148) of postoperative CQ considering a total of 14 variables was obtained, including additionally preoperative CQ, target refraction and previous surgeries.
Cataract surgery provides an improved functional vision in most of patients although this improvement can be limited by ocular comorbidities and complications. The relationship between PROMs and CROMs is multifactorial and complex.
在来自 10 个不同欧洲中心的大量患者中评估白内障手术的结果，描述患者报告的结局（PROMs）与临床医生报告的结局测量（CROMs）之间的关系。
这是一项前瞻性、非干预性、多中心观察性描述性研究，分析了 3799 例白内障手术患者的临床结局（平均年龄：72.7 岁）。在所有病例中，均使用国际健康结局测量联合会（ICHOM）制定的白内障手术标准来登记临床数据。术后 3 个月的视力和屈光数据被视为 CROMs，而 Rasch 校准项目 2（RCCQ2）和 Catquest-9SF 总评分（CQ）被视为 PROMs。
术后矫正视力（CDVA）达到 0.3 对数视力或更好的患者占 88.7%（2505/2823）。术前与术后 RCCQ2 和 CQ 评分的平均差值分别为-3.09 和-2.39。91.5%（2163/2364）的患者报告手术提高了视觉功能。术后 CDVA 与术后屈光、PROMs 和并发症呈显著（尽管较弱）相关（0.133≤r≤0.289，p<0.001）。考虑到 10 个变量，获得了一个预测术后 CDVA 的模型（R：0.254），包括术前 CDVA、不同的眼部合并症、年龄、性别和术中并发症。同样，考虑到总共 14 个变量，还获得了一个预测术后 CQ 的模型（R：0.148），包括术前 CQ、目标屈光和先前手术。
白内障手术为大多数患者提供了更好的功能性视力，尽管这种改善可能受到眼部合并症和并发症的限制。PROMs 与 CROMs 之间的关系是多因素和复杂的。
