Tsegaw Asamere, Alemu Shitaye, Dessie Abere, Patterson Christopher C, Parry Eldryd H O, Phillips David I W, Trimble Elisabeth R
Department of Ophthalmology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
J Ophthalmol. 2021 Mar 31;2021:6696548. doi: 10.1155/2021/6696548. eCollection 2021.
To investigate the level of diabetic retinopathy in type 2 diabetes (T2DM) patients attending the University of Gondar Hospital (UGH) Diabetic Clinic, Northwest Ethiopia.
An audit was carried out involving a total of 739 T2DM patients attending at the diabetic clinic of UGH. They represented approximately 90% and 50% of all T2DM patients under regular review at the urban and rural diabetic clinics of UGH, respectively. All were supervised by the same clinical team for a long period. Eye examinations were performed for visual acuity, cataract, and retinal changes (retinal photography and slit-lamp biomicroscopy). Body mass index (BMI) and HbA1c levels were measured. The presence or absence of hypertension was recorded.
Men constituted 41.5% of the group, the mean age at diagnosis of T2DM was 50.4 years, and 50.2% were hypertensive. The BMI was 25.0 ± 4.1 kg/m, and HbA1c was 7.75 ± 1.63% (61.2 ± 17.8 mmol/mol) (mean ± SD, for BMI and HbA1c)). Severe visual impairment/blindness was reported in 10.6%, 15.2% had cataract, 16.0% had retinopathy, and 11.1% had maculopathy. The prevalence of retinopathy increased with time from diagnosis of T2DM (chi-square for trend, < 0.001) and with increasing HbA1c level (chi-square for trend, =0.03).
These results compare well with the most recent results in well-equipped, wealthier regions of the world and show the importance of stable healthcare infrastructure for chronic-disease management.
调查埃塞俄比亚西北部贡德尔大学医院(UGH)糖尿病诊所2型糖尿病(T2DM)患者的糖尿病视网膜病变水平。
对UGH糖尿病诊所的739例T2DM患者进行了一项审计。他们分别约占UGH城乡糖尿病诊所定期复诊的所有T2DM患者的90%和50%。长期以来,所有患者均由同一临床团队进行监督。进行了视力、白内障和视网膜变化(视网膜摄影和裂隙灯生物显微镜检查)的眼部检查。测量了体重指数(BMI)和糖化血红蛋白(HbA1c)水平。记录高血压的有无。
男性占该组的41.5%,T2DM诊断时的平均年龄为50.4岁,50.2%的患者患有高血压。BMI为25.0±4.1kg/m,HbA1c为7.75±1.63%(61.2±17.8mmol/mol)(BMI和HbA1c的平均值±标准差)。报告有严重视力损害/失明的患者占10.6%,15.2%的患者有白内障,16.0%的患者有视网膜病变,11.1%的患者有黄斑病变。视网膜病变的患病率随T2DM诊断时间的延长而增加(趋势卡方检验,<0.001),并随HbA1c水平的升高而增加(趋势卡方检验,=0.03)。
这些结果与世界上设备更完善、更富裕地区的最新结果相当,表明稳定的医疗基础设施对慢性病管理的重要性。