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埃塞俄比亚西北部贡德尔大学医院糖尿病门诊2型糖尿病患者的糖尿病视网膜病变

Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients Attending the Diabetic Clinic of the University of Gondar Hospital, Northwest Ethiopia.

作者信息

Tsegaw Asamere, Alemu Shitaye, Dessie Abere, Patterson Christopher C, Parry Eldryd H O, Phillips David I W, Trimble Elisabeth R

机构信息

Department of Ophthalmology, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Department of Internal Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

出版信息

J Ophthalmol. 2021 Mar 31;2021:6696548. doi: 10.1155/2021/6696548. eCollection 2021.

Abstract

OBJECTIVE

To investigate the level of diabetic retinopathy in type 2 diabetes (T2DM) patients attending the University of Gondar Hospital (UGH) Diabetic Clinic, Northwest Ethiopia.

METHODS

An audit was carried out involving a total of 739 T2DM patients attending at the diabetic clinic of UGH. They represented approximately 90% and 50% of all T2DM patients under regular review at the urban and rural diabetic clinics of UGH, respectively. All were supervised by the same clinical team for a long period. Eye examinations were performed for visual acuity, cataract, and retinal changes (retinal photography and slit-lamp biomicroscopy). Body mass index (BMI) and HbA1c levels were measured. The presence or absence of hypertension was recorded.

RESULTS

Men constituted 41.5% of the group, the mean age at diagnosis of T2DM was 50.4 years, and 50.2% were hypertensive. The BMI was 25.0 ± 4.1 kg/m, and HbA1c was 7.75 ± 1.63% (61.2 ± 17.8 mmol/mol) (mean ± SD, for BMI and HbA1c)). Severe visual impairment/blindness was reported in 10.6%, 15.2% had cataract, 16.0% had retinopathy, and 11.1% had maculopathy. The prevalence of retinopathy increased with time from diagnosis of T2DM (chi-square for trend, < 0.001) and with increasing HbA1c level (chi-square for trend, =0.03).

CONCLUSION

These results compare well with the most recent results in well-equipped, wealthier regions of the world and show the importance of stable healthcare infrastructure for chronic-disease management.

摘要

目的

调查埃塞俄比亚西北部贡德尔大学医院(UGH)糖尿病诊所2型糖尿病(T2DM)患者的糖尿病视网膜病变水平。

方法

对UGH糖尿病诊所的739例T2DM患者进行了一项审计。他们分别约占UGH城乡糖尿病诊所定期复诊的所有T2DM患者的90%和50%。长期以来,所有患者均由同一临床团队进行监督。进行了视力、白内障和视网膜变化(视网膜摄影和裂隙灯生物显微镜检查)的眼部检查。测量了体重指数(BMI)和糖化血红蛋白(HbA1c)水平。记录高血压的有无。

结果

男性占该组的41.5%,T2DM诊断时的平均年龄为50.4岁,50.2%的患者患有高血压。BMI为25.0±4.1kg/m,HbA1c为7.75±1.63%(61.2±17.8mmol/mol)(BMI和HbA1c的平均值±标准差)。报告有严重视力损害/失明的患者占10.6%,15.2%的患者有白内障,16.0%的患者有视网膜病变,11.1%的患者有黄斑病变。视网膜病变的患病率随T2DM诊断时间的延长而增加(趋势卡方检验,<0.001),并随HbA1c水平的升高而增加(趋势卡方检验,=0.03)。

结论

这些结果与世界上设备更完善、更富裕地区的最新结果相当,表明稳定的医疗基础设施对慢性病管理的重要性。

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