前列腺癌患者神经节中生理性 Ga-PSMA-11 和 F-DCFPyL PET/CT 摄取的患者内比较：影像学研究。

Intra-patient comparison of physiologic Ga-PSMA-11 and F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay.

机构信息

Division of Nuclear Medicine, Department of Radiology, Saint Louis University Hospital, St. Louis, MO, USA.

Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO, USA.

出版信息

Cancer Imaging. 2021 Apr 16;21(1):35. doi: 10.1186/s40644-021-00404-8.

BACKGROUND

Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing Ga -PSMA-11 and in 96.9% of patients undergoing F-DCFPyL PET/CT examination. We have observed different patterns of ganglion visualization with F-DCFPyL compared to Ga-PSMA-11. This includes more frequent visualization of cervical and sacral ganglia, which may be attributable to better imaging characteristics with F PET imaging.

CASE PRESENTATION

This pictorial essay is to illustrate and compare, in the same patient, various representative cases of Ga-PSMA-11 and F-DCFPyL PET/CT uptake in ganglia at different anatomic locations, with different patterns and distribution of metabolic activity.

CONCLUSION

Reading physicians should be aware of the frequently encountered and occasionally different physiologic uptake of Ga-PSMA-11 and F DCFPyL in different ganglia.

背景

最近的研究报告称，在接受 Ga-PSMA-11 检查的患者中，有 98.5%至少有一个评估的神经节有代谢摄取，而在接受 F-DCFPyL PET/CT 检查的患者中，有 96.9%有代谢摄取。与 Ga-PSMA-11 相比，我们用 F-DCFPyL 观察到不同的神经节可视化模式。这包括更频繁地观察到颈神经节和骶神经节，这可能归因于 F PET 成像的更好的成像特性。