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前列腺癌患者神经节中生理性 Ga-PSMA-11 和 F-DCFPyL PET/CT 摄取的患者内比较：影像学研究。

Intra-patient comparison of physiologic Ga-PSMA-11 and F-DCFPyL PET/CT uptake in ganglia in prostate cancer patients: a pictorial essay.

机构信息

Division of Nuclear Medicine, Department of Radiology, Saint Louis University Hospital, St. Louis, MO, USA.

Mallinckrodt Institute of Radiology, Washington University, St. Louis, MO, USA.

出版信息

Cancer Imaging. 2021 Apr 16;21(1):35. doi: 10.1186/s40644-021-00404-8.

DOI:10.1186/s40644-021-00404-8
PMID:33863390
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8052677/
Abstract

BACKGROUND

Recent studies reported metabolic uptake in at least one of the evaluated ganglia in 98.5% of patients undergoing Ga -PSMA-11 and in 96.9% of patients undergoing F-DCFPyL PET/CT examination. We have observed different patterns of ganglion visualization with F-DCFPyL compared to Ga-PSMA-11. This includes more frequent visualization of cervical and sacral ganglia, which may be attributable to better imaging characteristics with F PET imaging.

CASE PRESENTATION

This pictorial essay is to illustrate and compare, in the same patient, various representative cases of Ga-PSMA-11 and F-DCFPyL PET/CT uptake in ganglia at different anatomic locations, with different patterns and distribution of metabolic activity.

CONCLUSION

Reading physicians should be aware of the frequently encountered and occasionally different physiologic uptake of Ga-PSMA-11 and F DCFPyL in different ganglia.

摘要

背景

最近的研究报告称，在接受 Ga-PSMA-11 检查的患者中，有 98.5%至少有一个评估的神经节有代谢摄取，而在接受 F-DCFPyL PET/CT 检查的患者中，有 96.9%有代谢摄取。与 Ga-PSMA-11 相比，我们用 F-DCFPyL 观察到不同的神经节可视化模式。这包括更频繁地观察到颈神经节和骶神经节，这可能归因于 F PET 成像的更好的成像特性。

病例介绍

本影像学文章旨在比较同一位患者在不同解剖部位的 Ga-PSMA-11 和 F-DCFPyL PET/CT 摄取的不同代表性病例，以说明和比较神经节代谢活性的不同模式和分布。

结论

阅读医生应该意识到 Ga-PSMA-11 和 F-DCFPyL 在不同神经节中经常遇到的、偶尔不同的生理性摄取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/432b61e12581/40644_2021_404_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/3a20a6794baf/40644_2021_404_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/d4004c032cc3/40644_2021_404_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/9246f393bbc3/40644_2021_404_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/5be04aa5a21b/40644_2021_404_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/72fd44041e58/40644_2021_404_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/364a4f05a85b/40644_2021_404_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/31f805f78148/40644_2021_404_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/c1bb26de5ec1/40644_2021_404_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/9030f183170c/40644_2021_404_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/6a23e758fb27/40644_2021_404_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/432b61e12581/40644_2021_404_Fig11_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/3a20a6794baf/40644_2021_404_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/d4004c032cc3/40644_2021_404_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/9246f393bbc3/40644_2021_404_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/5be04aa5a21b/40644_2021_404_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/72fd44041e58/40644_2021_404_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/364a4f05a85b/40644_2021_404_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/31f805f78148/40644_2021_404_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/c1bb26de5ec1/40644_2021_404_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/9030f183170c/40644_2021_404_Fig9_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/6a23e758fb27/40644_2021_404_Fig10_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae6/8052677/432b61e12581/40644_2021_404_Fig11_HTML.jpg

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The role of additional late PSMA-ligand PET/CT in the differentiation between lymph node metastases and ganglia.额外的晚期前列腺特异性膜抗原（PSMA）配体PET/CT在区分淋巴结转移和神经节中的作用
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