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化脓性汗腺炎恶变为鳞状细胞癌的治疗:三例病例报告

The management of hidradenitis suppurativa degenerating into squamous cell carcinoma: About three case reports.

作者信息

Atri Souhaib, Ben Mahmoud Ahmed, Zehani Alia, Chammakhi Amine, Rebai Wael, Kacem Montasser Jameleddine

机构信息

Department of Surgery A, Rabta Hosptial, Tunis, Tunisia.

Faculty of Medicine of Tunis, Tunis El Manar University, Tunis, Tunisia.

出版信息

Ann Med Surg (Lond). 2021 Mar 24;64:102239. doi: 10.1016/j.amsu.2021.102239. eCollection 2021 Apr.

DOI:10.1016/j.amsu.2021.102239
PMID:33868679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8040103/
Abstract

INTRODUCTION AND IMPORTANCE

Hidradenitis suppurativa (HS) is a chronic inflammatory and suppurative disease of the apocrine sweat glands. Its transformation into squamous cell carcinoma (SCC) is very rare.

CASE PRESENTATION

We describe 3 cases of males aged 57, 58 and 55-years-old. The diagnoses were confirmed by pathology examination in all cases. Two of our patients underwent extended and complete surgery. The first two patients died during the year after the diagnosis was established, the third one is still alive with no recurrence after one year of surgery.

CLINICAL DISCUSSION

Hidradenitis suppurativa mostly concerns perianal location and it targets mainly male patients with a multifactorial development. Surgical treatment consists of large excision. The SCC is associated with a high mortality rate.

CONCLUSION

Hidradenitis suppurativa needs early diagnosis and effective surgery. The transformation into squamous cell carcinoma is rare and and its management is challenging. Extended and complete excision is required with rigorous postoperative follow-up.

摘要

引言与重要性

化脓性汗腺炎(HS)是一种大汗腺的慢性炎症性化脓性疾病。其转变为鳞状细胞癌(SCC)极为罕见。

病例介绍

我们描述了3例年龄分别为57岁、58岁和55岁的男性患者。所有病例均经病理检查确诊。我们的2例患者接受了扩大根治性手术。前2例患者在确诊后一年内死亡,第3例患者术后一年仍存活且无复发。

临床讨论

化脓性汗腺炎主要累及肛周部位,主要针对多因素发病的男性患者。手术治疗包括广泛切除。鳞状细胞癌的死亡率很高。

结论

化脓性汗腺炎需要早期诊断和有效的手术治疗。转变为鳞状细胞癌的情况罕见,其治疗具有挑战性。需要进行扩大根治性切除并进行严格的术后随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/05abb551d32a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/e313af583d81/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/8711c0c37721/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/fd1507b9381b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/e5585a01c9a3/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/05abb551d32a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/e313af583d81/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/8711c0c37721/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/fd1507b9381b/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/e5585a01c9a3/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7771/8040103/05abb551d32a/gr5.jpg

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