College of Chemistry, Nanchang University, Nanchang, Jiangxi, 330088, China.
The National Engineering Research Center for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, China.
Adv Healthc Mater. 2021 Jul;10(13):e2100259. doi: 10.1002/adhm.202100259. Epub 2021 Apr 19.
Compared with traditional glasses, the comfortable and convenient contact lens (CL) has seen an upsurge among the public. However, due to the lack of antibacterial properties of ordinary CLs, the risk of eye infection is greatly increased accordingly. On the other hand, ordinary CLs also cannot effectively reduce the short-wavelength blue light emitted from electronic products, such as mobile phones and computers. Aiming at the above two problems, zinc oxide (ZnO)/cyclized polyacrylonitrile (CPAN) composites are developed for CL modification. After loading with ZnO/CPAN (ZC), the CL shows a broad-spectrum antibacterial property. Further experiments also prove that it can block UVB, UVA, as well as blue light selectively, under the premise of ensuring hydrophilicity and certain transparency. Theoretically, this ZC-decorated CL can fundamentally reduce the damage to the eyes from harmful light emitted by light-emitting diodes and the secretion of pro-inflammatory factors, which is thus a promising eye protection strategy for modern society.
与传统眼镜相比，舒适便捷的隐形眼镜（CL）在公众中掀起了热潮。然而，由于普通 CL 缺乏抗菌性能，眼睛感染的风险相应大大增加。另一方面，普通 CL 也不能有效减少来自电子产品（如手机和电脑）发出的短波长蓝光。针对上述两个问题，开发了氧化锌（ZnO）/环化聚丙烯腈（CPAN）复合材料用于 CL 改性。负载 ZnO/CPAN（ZC）后，CL 显示出广谱抗菌性能。进一步的实验还证明，在保证亲水性和一定透明度的前提下，它可以有选择地阻挡 UVB、UVA 和蓝光。从理论上讲，这种 ZC 修饰的 CL 可以从根本上减少发光二极管发出的有害光和促炎因子分泌对眼睛的损害，因此是现代社会有前途的眼睛保护策略。
