University of Colorado School of Medicine, Denver, Colo.
Novartis Pharmaceuticals Corporation, East Hanover, NJ.
J Allergy Clin Immunol Pract. 2021 Aug;9(8):3080-3088.e1. doi: 10.1016/j.jaip.2021.03.056. Epub 2021 Apr 16.
Discordance between physicians' and patients' perceptions of asthma control may negatively impact symptom control, treatment, and outcomes.
To evaluate concordance between physicians' and patients' perceptions of overall asthma control and the association between perceived overall control and individual components of control.
U.S. survey data (Dec 2015-Feb 2016; Apr-Aug 2018) from the Respiratory Disease Specific Programme were analyzed. Physicians recorded patient disease characteristics and their perception of patients' asthma control. Patients' perception of control was assessed using the Asthma Control Test; responses were compared with level of symptom control per the Global Initiative for Asthma criteria and Work Productivity and Impairment questionnaire responses. Agreement and association were assessed by weighted kappa (κ) and Spearman rho (ρ), respectively.
The study included 1,288 patients. Concordance between physician-perceived and patient-perceived asthma control in the prior 4 weeks was moderate (κ = 0.4951). Association between physicians' overall perception of asthma control and patients' overall Asthma Control Test score was also moderate (ρ = 0.5450). However, 61.5% of patients with self-reported, well-controlled asthma had shortness of breath 1 to 2 times/wk, 45.6% had 1 to 2 night-time awakenings/wk, and patients reported a mean (SD) daily activity impairment of 17.5% (16.2%). Only 21.8% of patients with self-reported, well-controlled asthma were classified as such by Global Initiative for Asthma symptom criteria.
Patients' self-assessment of overall control does not accurately characterize the true level of control; thus, patients and physicians may benefit from working together to assess the individual components of asthma control to achieve better disease management, treatment decisions, and improved outcomes.
医生和患者对哮喘控制的认知存在差异,可能会对症状控制、治疗和结局产生负面影响。
评估医生和患者对哮喘总体控制的认知是否一致,并评估感知的总体控制与控制的各个方面之间的关联。
对美国呼吸道疾病专项计划(2015 年 12 月至 2016 年 2 月;2018 年 4 月至 8 月)的调查数据进行分析。医生记录患者的疾病特征及其对患者哮喘控制的认知。患者对控制的认知通过哮喘控制测试(Asthma Control Test)进行评估;根据全球哮喘倡议(Global Initiative for Asthma)的标准和工作效率和障碍问卷的反应,将反应与症状控制水平进行比较。分别采用加权 Kappa(κ)和 Spearman rho(ρ)评估一致性和相关性。
研究纳入了 1288 名患者。在过去 4 周内,医生感知和患者感知的哮喘控制之间的一致性为中度(κ=0.4951)。医生对哮喘控制的整体感知与患者哮喘控制测试的整体评分之间也存在中度关联(ρ=0.5450)。然而,61.5%报告自我控制良好的哮喘患者每周有 1-2 次呼吸急促,45.6%每周有 1-2 次夜间觉醒,患者报告的日常活动障碍平均(SD)为 17.5%(16.2%)。只有 21.8%自我报告控制良好的哮喘患者符合全球哮喘倡议的症状标准。
患者对整体控制的自我评估不能准确描述真正的控制水平;因此,患者和医生可能会受益于共同评估哮喘控制的各个方面,以实现更好的疾病管理、治疗决策和改善结局。