Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.
Department of Clinical and Health Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria.
Psychol Med. 2021 May;51(7):1057-1067. doi: 10.1017/S0033291721001355. Epub 2021 Apr 20.
Given the widespread nature and clinical consequences of self-harm and suicidal ideation among adolescents, establishing the efficacy of developmentally appropriate treatments that reduce both self-harm and suicidal ideation in the context of broader adolescent psychopathology is critical.
We conducted a systematic review and meta-analysis of the Dialectical Behaviour Therapy for Adolescents (DBT-A) literature on treating self-injury in adolescents (12-19 years). We searched for eligible trials and treatment evaluations published prior to July 2020 in MEDLINE/PubMed, Scopus, Google Scholar, EMBASE, and the Cochrane Library databases for clinical trials. Twenty-one studies were identified [five randomized-controlled trials (RCTs), three controlled clinical trials (CCTs), and 13 pre-post evaluations]. We extracted data for predefined primary (self-harm, suicidal ideation) and secondary outcomes (borderline personality symptoms; BPD) and calculated treatment effects for RCTs/CCTs and pre-post evaluations. This meta-analysis was pre-registered with OSF: osf.io/v83e7.
Overall, the studies comprised 1673 adolescents. Compared to control groups, DBT-A showed small to moderate effects for reducing self-harm (g = -0.44; 95% CI -0.81 to -0.07) and suicidal ideation (g = -0.31, 95% CI -0.52 to -0.09). Pre-post evaluations suggested large effects for all outcomes (self-harm: g = -0.98, 95% CI -1.15 to -0.81; suicidal ideation: g = -1.16, 95% CI -1.51 to -0.80; BPD symptoms: g = -0.97, 95% CI -1.31 to -0.63).
DBT-A appears to be a valuable treatment in reducing both adolescent self-harm and suicidal ideation. However, evidence that DBT-A reduces BPD symptoms was only found in pre-post evaluations.
鉴于青少年自残和自杀意念的广泛存在及其临床后果,在更广泛的青少年精神病理学背景下,确定能够减少自残和自杀意念的发展适当治疗的疗效至关重要。
我们对青少年(12-19 岁)接受的青少年辩证行为治疗(DBT-A)治疗自残的文献进行了系统评价和荟萃分析。我们在 MEDLINE/PubMed、Scopus、Google Scholar、EMBASE 和 Cochrane 图书馆数据库中搜索了 2020 年 7 月之前发表的合格试验和治疗评估,以寻找临床试验。确定了 21 项研究[五项随机对照试验(RCT),三项对照临床试验(CCT)和 13 项前后评估]。我们为预定义的主要(自残,自杀意念)和次要结局(边缘型人格症状;BPD)提取了数据,并计算了 RCT/CCT 和前后评估的治疗效果。该荟萃分析已在 OSF 上预先注册:osf.io/v83e7。
总体而言,这些研究包括 1673 名青少年。与对照组相比,DBT-A 减少自残(g = -0.44;95%CI -0.81 至 -0.07)和自杀意念(g = -0.31,95%CI -0.52 至 -0.09)的效果为小至中等。前后评估表明,所有结局的效果都很大(自残:g = -0.98,95%CI -1.15 至 -0.81;自杀意念:g = -1.16,95%CI -1.51 至 -0.80;BPD 症状:g = -0.97,95%CI -1.31 至 -0.63)。
DBT-A 似乎是一种有价值的治疗方法,可以减少青少年自残和自杀意念。然而,仅在前后评估中发现 DBT-A 可减少 BPD 症状的证据。