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辩证行为疗法治疗青少年自残和自杀意念的疗效:系统评价和荟萃分析。

Efficacy of dialectical behavior therapy for adolescent self-harm and suicidal ideation: a systematic review and meta-analysis.

机构信息

Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria.

Department of Clinical and Health Psychology, Faculty of Psychology, University of Vienna, Vienna, Austria.

出版信息

Psychol Med. 2021 May;51(7):1057-1067. doi: 10.1017/S0033291721001355. Epub 2021 Apr 20.

Abstract

BACKGROUND

Given the widespread nature and clinical consequences of self-harm and suicidal ideation among adolescents, establishing the efficacy of developmentally appropriate treatments that reduce both self-harm and suicidal ideation in the context of broader adolescent psychopathology is critical.

METHODS

We conducted a systematic review and meta-analysis of the Dialectical Behaviour Therapy for Adolescents (DBT-A) literature on treating self-injury in adolescents (12-19 years). We searched for eligible trials and treatment evaluations published prior to July 2020 in MEDLINE/PubMed, Scopus, Google Scholar, EMBASE, and the Cochrane Library databases for clinical trials. Twenty-one studies were identified [five randomized-controlled trials (RCTs), three controlled clinical trials (CCTs), and 13 pre-post evaluations]. We extracted data for predefined primary (self-harm, suicidal ideation) and secondary outcomes (borderline personality symptoms; BPD) and calculated treatment effects for RCTs/CCTs and pre-post evaluations. This meta-analysis was pre-registered with OSF: osf.io/v83e7.

RESULTS

Overall, the studies comprised 1673 adolescents. Compared to control groups, DBT-A showed small to moderate effects for reducing self-harm (g = -0.44; 95% CI -0.81 to -0.07) and suicidal ideation (g = -0.31, 95% CI -0.52 to -0.09). Pre-post evaluations suggested large effects for all outcomes (self-harm: g = -0.98, 95% CI -1.15 to -0.81; suicidal ideation: g = -1.16, 95% CI -1.51 to -0.80; BPD symptoms: g = -0.97, 95% CI -1.31 to -0.63).

CONCLUSIONS

DBT-A appears to be a valuable treatment in reducing both adolescent self-harm and suicidal ideation. However, evidence that DBT-A reduces BPD symptoms was only found in pre-post evaluations.

摘要

背景

鉴于青少年自残和自杀意念的广泛存在及其临床后果,在更广泛的青少年精神病理学背景下,确定能够减少自残和自杀意念的发展适当治疗的疗效至关重要。

方法

我们对青少年(12-19 岁)接受的青少年辩证行为治疗(DBT-A)治疗自残的文献进行了系统评价和荟萃分析。我们在 MEDLINE/PubMed、Scopus、Google Scholar、EMBASE 和 Cochrane 图书馆数据库中搜索了 2020 年 7 月之前发表的合格试验和治疗评估,以寻找临床试验。确定了 21 项研究[五项随机对照试验(RCT),三项对照临床试验(CCT)和 13 项前后评估]。我们为预定义的主要(自残,自杀意念)和次要结局(边缘型人格症状;BPD)提取了数据,并计算了 RCT/CCT 和前后评估的治疗效果。该荟萃分析已在 OSF 上预先注册:osf.io/v83e7。

结果

总体而言,这些研究包括 1673 名青少年。与对照组相比,DBT-A 减少自残(g = -0.44;95%CI -0.81 至 -0.07)和自杀意念(g = -0.31,95%CI -0.52 至 -0.09)的效果为小至中等。前后评估表明,所有结局的效果都很大(自残:g = -0.98,95%CI -1.15 至 -0.81;自杀意念:g = -1.16,95%CI -1.51 至 -0.80;BPD 症状:g = -0.97,95%CI -1.31 至 -0.63)。

结论

DBT-A 似乎是一种有价值的治疗方法,可以减少青少年自残和自杀意念。然而,仅在前后评估中发现 DBT-A 可减少 BPD 症状的证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/783b/8188531/cc63026b969d/S0033291721001355_fig1.jpg

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