Department of Women and Children's Health, Hospital for Children and Adolescents and Center for Pediatric Research (CPL), Leipzig University, Liebigstrasse 20a, 04103, Leipzig, Germany.
LIFE Leipzig Research Center for Civilization Diseases, Leipzig University, Philipp-Rosenthal-Strasse 27, 04103, Leipzig, Germany.
BMC Pediatr. 2021 Apr 23;21(1):197. doi: 10.1186/s12887-021-02663-7.
Atopic diseases and behavioural difficulties in children have both been on the rise in recent decades. This study seeks to assess associations between atopic diseases and behavioural difficulties, examining the differences considering child age and how behavioural difficulties were reported (via self-report or parent-report).
Data on behavioural difficulties, assessed through the Strengths and Difficulties Questionnaire (SDQ), and on atopic diseases, assessed through the participant's medical history, were available for 2701 study participants aged 3 to 18 years. Associations between atopic diseases and behavioural difficulties were evaluated using linear regression analyses. We split the study sample into two groups. I: 3-to 10-year-olds/parent-reported SDQ (n = 1764), II: 11- to 18-year-olds/parent-reported SDQ (n = 937) and self-reported SDQ (n = 915). All analyses were adjusted for age, gender, and socioeconomic status.
In younger children, atopic dermatitis was strongly associated with higher total difficulties scores, more emotional problems and conduct problems, and more symptoms of hyperactivity/inattention. Parents reported higher total difficulties scores, more emotional problems, and more peer-relationship problems for adolescents with bronchial asthma and other allergies, whereas the adolescents themselves reported more peer relationship problems.
In younger children, atopic dermatitis is associated with internalizing and externalizing problems. In adolescents, bronchial asthma and other allergies are associated with a greater level of internalizing problems only. The findings further suggest that parents of adolescents are more likely to perceive associations between atopic diseases and behavioural difficulties than the adolescents themselves.
近几十年来，儿童特应性疾病和行为困难的发病率都有所上升。本研究旨在评估特应性疾病与行为困难之间的关联，同时考虑到儿童年龄和行为困难报告方式（自我报告或家长报告）的差异。
本研究共有 2701 名 3 至 18 岁的参与者，他们的数据包括通过《长处与困难问卷》（SDQ）评估的行为困难，以及通过参与者的病史评估的特应性疾病。使用线性回归分析评估特应性疾病与行为困难之间的关联。我们将研究样本分为两组。I 组：3 至 10 岁/家长报告的 SDQ（n=1764），II 组：11 至 18 岁/家长报告的 SDQ（n=937）和自我报告的 SDQ（n=915）。所有分析均调整了年龄、性别和社会经济地位。
在年幼的儿童中，特应性皮炎与更高的总分、更多的情绪问题和行为问题以及更多的多动/注意力不集中症状密切相关。父母报告患有支气管哮喘和其他过敏症的青少年总分、更多的情绪问题和更多的同伴关系问题更高，而青少年自身则报告了更多的同伴关系问题。
在年幼的儿童中，特应性皮炎与内化和外化问题有关。在青少年中，支气管哮喘和其他过敏症仅与更严重的内化问题有关。研究结果进一步表明，青少年的父母比青少年自身更有可能感知特应性疾病与行为困难之间的关联。
