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大型牙科诊所中新型冠状病毒污染风险的计算机模拟

Computer simulation of the SARS-CoV-2 contamination risk in a large dental clinic.

作者信息

Komperda Jonathan, Peyvan Ahmad, Li Dongru, Kashir Babak, Yarin Alexander L, Megaridis Constantine M, Mirbod Parisa, Paprotny Igor, Cooper Lyndon F, Rowan Susan, Stanford Clark, Mashayek Farzad

机构信息

Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, USA.

Department of Electrical and Computer Engineering, University of Illinois at Chicago, Chicago, Illinois 60607, USA.

出版信息

Phys Fluids (1994). 2021 Mar;33(3):033328. doi: 10.1063/5.0043934. Epub 2021 Mar 29.

DOI:10.1063/5.0043934
PMID:33897241
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8060974/
Abstract

COVID-19, caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) virus, has been rapidly spreading worldwide since December 2019, causing a public health crisis. Recent studies showed SARS-CoV-2's ability to infect humans via airborne routes. These motivated the study of aerosol and airborne droplet transmission in a variety of settings. This study performs a large-scale numerical simulation of a real-world dentistry clinic that contains aerosol-generating procedures. The simulation tracks the dispersion of evaporating droplets emitted during ultrasonic dental scaling procedures. The simulation considers 25 patient treatment cubicles in an open plan dentistry clinic. The droplets are modeled as having a volatile (evaporating) and nonvolatile fraction composed of virions, saliva, and impurities from the irrigant water supply. The simulated clinic's boundary and flow conditions are validated against experimental measurements of the real clinic. The results evaluate the behavior of large droplets and aerosols. We investigate droplet residence time and travel distance for different droplet diameters, surface contamination due to droplet settling and deposition, airborne aerosol mass concentration, and the quantity of droplets that escape through ventilation. The simulation results raise concerns due to the aerosols' long residence times (averaging up to 7.31 min) and travel distances (averaging up to 24.45 m) that exceed social distancing guidelines. Finally, the results show that contamination extends beyond the immediate patient treatment areas, requiring additional surface disinfection in the clinic. The results presented in this research may be used to establish safer dental clinic operating procedures, especially if paired with future supplementary material concerning the aerosol viral load generated by ultrasonic scaling and the viral load thresholds required to infect humans.

摘要

2019年12月以来,由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引起的新型冠状病毒肺炎(COVID-19)在全球迅速传播,引发了一场公共卫生危机。最近的研究表明,SARS-CoV-2具有通过空气传播途径感染人类的能力。这些研究促使人们对各种环境中的气溶胶和飞沫传播进行研究。本研究对一家包含气溶胶生成操作的真实牙科诊所进行了大规模数值模拟。该模拟跟踪了超声洁牙过程中喷出的蒸发液滴的扩散情况。模拟考虑了一家开放式牙科诊所中的25个患者治疗隔间。液滴被建模为由病毒粒子、唾液和来自冲洗水源的杂质组成的挥发性(蒸发)和非挥发性部分。模拟诊所的边界和流动条件根据真实诊所的实验测量结果进行了验证。结果评估了大液滴和气溶胶的行为。我们研究了不同液滴直径下的液滴停留时间和传播距离、液滴沉降和沉积导致的表面污染、空气中气溶胶质量浓度以及通过通风口逸出的液滴数量。模拟结果令人担忧,因为气溶胶的停留时间较长(平均可达7.31分钟),传播距离较远(平均可达24.45米),超过了社交距离指导原则。最后,结果表明污染范围超出了直接的患者治疗区域,需要对诊所进行额外的表面消毒。本研究提出的结果可用于建立更安全的牙科诊所操作程序,特别是如果与未来关于超声洁牙产生的气溶胶病毒载量以及感染人类所需的病毒载量阈值的补充材料相结合。

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本文引用的文献

1
Numerical modeling of the distribution of virus carrying saliva droplets during sneeze and cough.打喷嚏和咳嗽时携带病毒的唾液飞沫分布的数值模拟。
Phys Fluids (1994). 2020 Aug 1;32(8):083305. doi: 10.1063/5.0018432. Epub 2020 Aug 11.
2
On airborne virus transmission in elevators and confined spaces.关于电梯和密闭空间中的空气传播病毒
Phys Fluids (1994). 2021 Jan 1;33(1):011905. doi: 10.1063/5.0038180. Epub 2021 Jan 26.
3
Disease transmission through expiratory aerosols on an urban bus.城市公交车上通过呼气气溶胶传播疾病。
牙科模拟头模实验室中牙科设备水线的定期检测与消毒维护
Sci Rep. 2025 Feb 12;15(1):5234. doi: 10.1038/s41598-025-89010-3.
4
Aerosol Dispersion and Efficacy of Protective Strategies During Dental Procedures.牙科手术期间气溶胶的扩散及防护策略的效果
Int Dent J. 2025 Jun;75(3):1906-1912. doi: 10.1016/j.identj.2025.01.015. Epub 2025 Feb 12.
5
Reduction of aerosol and droplet dispersions using intraoral and extraoral vacuums for dental treatments with face-up, diagonal and upright positions.采用口内和口外吸引器减少牙科治疗中仰卧、斜向和垂直位时气溶胶和液滴的分散。
BMC Oral Health. 2024 Nov 17;24(1):1397. doi: 10.1186/s12903-024-04911-5.
6
Concern about the risk of aerosol contamination from ultrasonic scaler: a systematic review and meta-analysis.关注超声洁牙机气溶胶污染的风险:系统评价和荟萃分析。
BMC Oral Health. 2024 Apr 5;24(1):417. doi: 10.1186/s12903-024-03996-2.
7
Precise control of digital dental unit to reduce aerosol and splatter production: new challenges for future epidemics.精确控制数字牙科设备以减少气溶胶和喷溅产生:未来传染病的新挑战。
BMC Oral Health. 2024 Feb 10;24(1):213. doi: 10.1186/s12903-024-03980-w.
8
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J Dent Res. 2023 Aug;102(9):1031-1037. doi: 10.1177/00220345231169434. Epub 2023 May 29.
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Estimating the restraint of SARS-CoV-2 spread using a conventional medical air-cleaning device: Based on an experiment in a typical dental clinical setting.利用常规医用空气净化设备估算 SARS-CoV-2 传播的抑制效果:基于典型牙科临床环境下的实验。
Int J Hyg Environ Health. 2023 Mar;248:114120. doi: 10.1016/j.ijheh.2023.114120. Epub 2023 Jan 27.
Phys Fluids (1994). 2021 Jan 1;33(1):015116. doi: 10.1063/5.0037452. Epub 2021 Jan 12.
4
Jet fans in the underground car parking areas and virus transmission.地下停车场的射流风机与病毒传播
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5
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Phys Fluids (1994). 2021 Jan 1;33(1):013309. doi: 10.1063/5.0038562. Epub 2021 Jan 15.
6
Simulation of a vacuum helmet to contain pathogen-bearing droplets in dental and otolaryngologic outpatient interventions.用于在牙科和耳鼻喉科门诊干预中容纳携带病原体飞沫的真空头盔的模拟。
Phys Fluids (1994). 2021 Jan 1;33(1):013307. doi: 10.1063/5.0036749. Epub 2021 Jan 12.
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Phys Fluids (1994). 2020 Dec 1;32(12):127112. doi: 10.1063/5.0035072.
8
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Phys Fluids (1994). 2020 Dec 1;32(12):121707. doi: 10.1063/5.0035701.
9
Effects of space sizes on the dispersion of cough-generated droplets from a walking person.空间大小对行走者咳嗽产生的飞沫扩散的影响。
Phys Fluids (1994). 2020 Dec 1;32(12):121705. doi: 10.1063/5.0034874.
10
Assessment of Air Contamination by SARS-CoV-2 in Hospital Settings.医院环境中 SARS-CoV-2 空气污染物评估。
JAMA Netw Open. 2020 Dec 1;3(12):e2033232. doi: 10.1001/jamanetworkopen.2020.33232.