Gao Jie, Zeng Li, Yao Linlin, Wang Ziniu, Yang Xiaoxi, Shi Jianbo, Hu Ligang, Liu Qian, Chen Chunying, Xia Tian, Qu Guangbo, Zhang Xian-En, Jiang Guibin
State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.
University of Chinese Academy of Sciences, Beijing 100049, China.
Nano Today. 2021 Aug;39:101161. doi: 10.1016/j.nantod.2021.101161. Epub 2021 Apr 17.
The family of coronavirus are named for their crown shape. Encoded by the genetic material inherited from the coronavirus itself, this intrinsic well-known "viral corona" is considered an "inherited corona". After contact with mucosa or the entrance into the host, bare coronaviruses can become covered by a group of dissolved biomolecules to form one or multiple layers of biomolecules. The layers acquired from the surrounding environment are named the "acquired corona". We highlight here the possible role of the acquired corona in the pathogenesis of coronaviruses, which will generate fresh insight into the nature of various coronavirus-host interactions.
冠状病毒家族因其冠状外形而得名。这种固有的、众所周知的“病毒冠”由冠状病毒自身遗传的遗传物质编码，被认为是一种“遗传冠”。在与黏膜接触或进入宿主后，裸露的冠状病毒会被一组溶解的生物分子覆盖，形成一层或多层生物分子。从周围环境中获得的这些层被称为“获得性冠”。我们在此强调获得性冠在冠状病毒发病机制中可能发挥的作用，这将为各种冠状病毒与宿主相互作用的本质带来新的见解。
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