Orhan Nilufer, Gökbulut Alper, Deliorman Orhan Didem
Gazi University Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey
Ankara University Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey
Turk J Pharm Sci. 2021 Apr 20;18(2):204-212. doi: 10.4274/tjps.galenos.2020.12258.
In Turkey, the genus Lehm. is represented by two species, namely Boiss. and (Willd.) Lehm., which are used as both food and for medicinal purposes. This study aimed to evaluate the antidiabetic and antioxidant potential and phytochemical profiles of leaf, flower, and root extracts of species.
α-Glucosidase and α-amylase inhibitory activities, antioxidant effects, and total phenol and flavonoid contents of extracts were evaluated. High-performance liquid chromatography was performed for identifying and quantifying phenolic compounds, which are responsible for various activities of these extracts.
Among the investigated phenolic compounds, caffeic and rosmarinic acids and rutin were determined and quantified in methanol extracts. Rutin was the major compound in the flower extract of . Rutin and rosmarinic acid were the major compounds in the leaf extract of . The flowers, leaves and roots of were also rich in rosmarinic acid. The antioxidant and antidiabetic potential of these extracts may be attributable to their rutin and rosmarinic acid content.
species can be used as natural sources of antioxidants. Notably, extracts can be used for the development of herbal products with antidiabetic potential.
在土耳其，Lehm.属有两个物种代表，即Boiss.和(Willd.) Lehm.，它们既被用作食物，也被用于药用。本研究旨在评估该物种叶、花和根提取物的抗糖尿病和抗氧化潜力以及植物化学特征。
评估了提取物的α-葡萄糖苷酶和α-淀粉酶抑制活性、抗氧化作用以及总酚和黄酮含量。采用高效液相色谱法鉴定和定量负责这些提取物各种活性的酚类化合物。
在所研究的酚类化合物中，在甲醇提取物中测定并定量了咖啡酸、迷迭香酸和芦丁。芦丁是该物种花提取物中的主要化合物。芦丁和迷迭香酸是该物种叶提取物中的主要化合物。该物种的花、叶和根中也富含迷迭香酸。这些提取物的抗氧化和抗糖尿病潜力可能归因于它们的芦丁和迷迭香酸含量。
该物种可作为抗氧化剂的天然来源。值得注意的是，该物种提取物可用于开发具有抗糖尿病潜力的草药产品。
