1例HTLV1感染患者的小细胞肺表皮样癌：病例报告及文献复习

Small cells lung epidermoid carcinoma in a HTLV1-infected patient: case report and literature review.

作者信息

Dahy Flávia Esper, Palhares Renata Basic, Assone Tatiane, Smid Jerusa, Moura João Victor Luisi de, Haziot Michel E J, Marcusso Rosa Maria N, Oliveira Augusto César Penalva de, Casseb Jorge

机构信息

Instituto de Infectologia Emílio Ribas, São Paulo, São Paulo, Brazil.

Universidade de São Paulo, Faculdade de Medicina, Laboratório de Investigação Médica em Neurologia (LIM 56), São Paulo, São Paulo, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2021 Apr 26;63:e35. doi: 10.1590/S1678-9946202163035. eCollection 2021.

DOI:10.1590/S1678-9946202163035

PMID:33909849

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8075617/

Abstract

The human T cell lymphotropic virus type 1 (HTLV-1) is the first human retrovirus discovered. Since then, it has spread worldwide and is mainly associated with adult T cell leukemia/lymphoma (ATLL) and HTLV1-associated myelopathy (HAM). Its relationship, however, with other types of cancer is controversial. We describe the case of a patient presenting with small cells lung epidermoid carcinoma who had recently developed HAM, and a review of the literature related to these conditions. This is the first case of this type of lung cancer, the same of the first description in the literature, associated with HAM outside Japan.

摘要

人类嗜T细胞病毒1型（HTLV-1）是发现的第一种人类逆转录病毒。自那时起，它已在全球传播，主要与成人T细胞白血病/淋巴瘤（ATLL）和HTLV-1相关脊髓病（HAM）有关。然而，它与其他类型癌症的关系存在争议。我们描述了一名患有小细胞肺表皮样癌且近期患上HAM的患者病例，并对与这些病症相关的文献进行了综述。这是此类肺癌的首例，也是文献中首例在日本境外与HAM相关的病例描述。