Akçay Gürbüz, Topal Yaşar, Aydın Osman
Department of Pediatrics, Pamukkale University Faculty of Medicine, Denizli, (The work was carried out at Denizli MediKlinik Hospital), Mugla, Turkey.
Department of Pediatrics, Muğla Sıtkı Koçman University Faculty of Medicine, Muğla, Turkey.
Indian J Dermatol. 2021 Jan-Feb;66(1):49-54. doi: 10.4103/ijd.IJD_324_19.
Terra firma-forme dermatosis (TFFD) is a clinical condition that may be defined as a dirty appearance of skin. Although it has been defined for many years, its clinical value is not well known.
We aimed to determine the prevalence of allergic disorders (asthma, allergic rhinitis, and eczema) to investigate if this clinical condition is associated with allergic disorders in children with TFFD.
A questionnaire descriptive of allergic disorders [International Study of Asthma and Allergies in Children (ISAAC)] was applied to all children diagnosed with TFFD at the pediatric clinics during a 6-month period specified for the study. The results were compared with the two ISAAC studies that have been previously conducted in our region.
The prevalence of TFFD among 1695 children examined at our outpatient clinic was found to be 3.18% ( = 54). The youngest of the children was 6 months old and the oldest 13 years, with an average age of 6.08 ± 2.69 years. Our study group had significantly greater rates and intensities of lifetime wheezing, wheezing in the last 12 months (current wheezing), lifetime allergic rhinitis, allergic rhinitis in the last 12 months; and the rate of physician-diagnosed allergic rhinitis compared to the comparator groups ( < 0.005).
The results support the view that TFFD may be a sign of associated asthma and allergic rhinitis.
地衣状皮肤病变(TFFD)是一种临床病症,其可被定义为皮肤外观脏污。尽管其已被定义多年,但其临床价值尚不为人所知。
我们旨在确定过敏性疾病(哮喘、过敏性鼻炎和湿疹)的患病率,以调查这种临床病症是否与患有TFFD的儿童的过敏性疾病相关。
在为该研究指定的6个月期间,向儿科诊所所有被诊断为TFFD的儿童发放了一份关于过敏性疾病的问卷[儿童哮喘和过敏国际研究(ISAAC)]。将结果与之前在我们地区进行的两项ISAAC研究进行比较。
在我们门诊检查的1695名儿童中,TFFD的患病率为3.18%(n = 54)。年龄最小的儿童为6个月,最大的为13岁,平均年龄为6.08±2.69岁。与对照组相比,我们的研究组在终身喘息、过去12个月内的喘息(当前喘息)、终身过敏性鼻炎、过去12个月内的过敏性鼻炎;以及医生诊断的过敏性鼻炎的发生率和严重程度方面显著更高(P < 0.005)。
结果支持TFFD可能是相关哮喘和过敏性鼻炎的一个迹象这一观点。