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城市印度人群中干眼症症状的流行情况。

Prevalence of symptoms of dry eye disease in an urban Indian population.

机构信息

Cornea and Anterior Segment Services, MGM Eye Institute, Raipur, Chhattisgarh, India.

出版信息

Indian J Ophthalmol. 2021 May;69(5):1061-1066. doi: 10.4103/ijo.IJO_1796_20.

Abstract

PURPOSE

The aim of this study was to estimate the prevalence of symptoms of dry eye disease (DED) in an urban population in India.

METHODS

In this cross-sectional study, a two-stage cluster sampling procedure was conducted across 50 municipal wards in the city of Raipur, India, between December 2019 and February 2020, to include 2500 households. Interviewers collected demographic and lifestyle data from participants aged ≥20 years. DED symptoms were assessed using a standard six-item validated questionnaire. The presence of one or more of the six dry eye symptoms often or all the time was considered positive for DED symptoms.

RESULTS

In this study, 2378 people completed the survey of whom 1397 (58.7%) were males and 981 (41.3%) were females. The crude and overall age-adjusted prevalence for any positive symptom was 6.5% and 6.8% (95% CI: 5.8-7.8%), respectively. The commonest symptom was red eyes (2.8%) followed by burning sensation (1.8%), foreign body sensation (1.7%), dry eyes (1.2%), gummy eyes (1.2%), and crusts on eyelashes (0.8%). The associated risk factors were female sex, use of digital display, smoking and stay in an air-conditioned environment.

CONCLUSION

The prevalence of DED symptoms in this urban Indian population was less than the prevalence reported in most other population-based studies from outside India, and lower than other hospital-based studies from India. Hence, DED prevalence in India is either lower than current estimates or is non-uniform in distribution.

摘要

目的

本研究旨在评估印度城市人口中干眼症(DED)症状的患病率。

方法

在这项横断面研究中,2019 年 12 月至 2020 年 2 月,在印度赖布尔市的 50 个市政区进行了两阶段聚类抽样,共纳入 2500 户家庭。调查员从 20 岁及以上的参与者中收集人口统计学和生活方式数据。使用经过验证的六分量表评估 DED 症状。出现六种干眼症状中的一种或多种且经常或总是存在被认为有 DED 症状。

结果

在这项研究中,共有 2378 人完成了调查,其中 1397 人(58.7%)为男性,981 人(41.3%)为女性。未校正和总体年龄校正后任何阳性症状的患病率分别为 6.5%和 6.8%(95%CI:5.8-7.8%)。最常见的症状是眼红(2.8%),其次是烧灼感(1.8%)、异物感(1.7%)、眼睛干涩(1.2%)、眼睛发粘(1.2%)和睫毛上有鳞屑(0.8%)。相关的危险因素是女性、使用数字显示器、吸烟和处于空调环境中。

结论

在这个印度城市人群中,DED 症状的患病率低于印度以外的大多数其他基于人群的研究报告的患病率,也低于印度的其他基于医院的研究。因此,印度的 DED 患病率要么低于目前的估计,要么分布不均。

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