Sbricoli Luca, Cerrato Alessia, Frigo Anna Chiara, Zanette Gastone, Bacci Christian
Department of Neurosciences, Section of Clinical Dentistry, Unit of Oral Surgery and Pathology, University of Padova, 35122 Padova, Italy.
Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padova, 35122 Padova, Italy.
Dent J (Basel). 2021 Apr 1;9(4):40. doi: 10.3390/dj9040040.
The present study aimed to ascertain whether any significant reduction in patients' postoperative pain and inflammation could be achieved by using sterile physiological solution instead of normal water to irrigate the surgical field and cool the dental bur during third molar extractions.
The study concerned 22 patients (11 females and 11 males) in good general health, who were referred to the Dental Clinic at Padova University hospital for lower third molar extractions. They were randomly assigned to two groups. Only the fluid used to irrigate the surgical field and cool the dental bur differed between the two study groups, being sterile physiological solution for group A, and mains water for group B. Postoperative pain, swelling, trismus and inflammation with high sensitivity CRP where measured and statistically evaluated. The numerosity of our sample was calculated on the grounds of an endpoint based on data in the literature.
Eighteen patients needed bilateral extractions, and 4 required only one extraction, so a total of 40 third molars were extracted. A sterile physiological solution was used to irrigate the surgical field in 20 extractions, while water was used in the other 20 cases. Data analysis with Wilcoxon test show no differences between the two groups ( < 0.05).
no differences between groups for any of the parameters considered, after third molar extraction procedures undertaken using either sterile physiological solution or water for irrigation and cooling purposes.
本研究旨在确定在拔除第三磨牙时，使用无菌生理盐水而非普通水冲洗手术区域并冷却牙钻，是否能显著减轻患者术后的疼痛和炎症。
该研究涉及22例全身健康状况良好的患者（11名女性和11名男性），他们因下颌第三磨牙拔除被转诊至帕多瓦大学医院牙科诊所。他们被随机分为两组。两组之间仅用于冲洗手术区域和冷却牙钻的液体不同，A组使用无菌生理盐水，B组使用自来水。对术后疼痛、肿胀、牙关紧闭以及高敏CRP炎症进行测量并进行统计学评估。我们样本的数量是根据基于文献数据的一个终点来计算的。
18例患者需要双侧拔牙，4例仅需单侧拔牙，因此共拔除40颗第三磨牙。20次拔牙使用无菌生理盐水冲洗手术区域，另外20例使用水冲洗。采用Wilcoxon检验进行数据分析，结果显示两组之间无差异（<0.05）。
在使用无菌生理盐水或水进行冲洗和冷却的第三磨牙拔除手术后，所考虑的任何参数在两组之间均无差异。
