Dávila-Sánchez Andrés, Gutierrez Mario Felipe, Bermudez Jorge Pailover, Méndez-Bauer Luján, Pulido Camilo, Kiratzc Fagner, Alegria-Acevedo Luisa Fernanda, Farago Paulo Vitor, Loguercio Alessandro Dourado, Sauro Salvatore, Arrais Cesar Augusto Galvão
Universidad San Francisco de Quito USFQ, Departmento de Odontología Restauradora y Materiales Dentales, Escuela de Odontología, Pampite y Diego de Robles, Quito 170901, Ecuador.
Universidad de los Andes, Chile, Facultad de Odontología, Monseñor Álvaro del Portillo 12455, Santiago 7550000, Chile.
Polymers (Basel). 2021 Apr 2;13(7):1145. doi: 10.3390/polym13071145.
The aim of the present study was to evaluate the influence of several experimental pretreatment crosslinker solutions on the resin polymer-dentine interface created using a representative universal adhesive system, by means of microtensile bond strength testing (μTBS), nanomechanical properties and ultramorphology confocal laser scanning microscopy (CLSM). Five experimental solutions containing different flavonoids were applied as dentine pretreatment after acid etching. A control pretreatment group containing no flavonoid was also employed. A representative modern universal adhesive was then applied, followed by a 3 mm thick composite built up. Specimens were sectioned into sticks and submitted to a μTBS test or nanoindentation analysis along the interface (24 h or 25,000 thermocycles). The ultramorphology of the polymer-resin interface was also evaluated using CLSM. The results were analyzed using two-way ANOVA and Bonferroni's post hoc test (α = 0.05). All flavonoids improved short- and long-term μTBS values ( < 0.01), while only some specific such solutions improved the nanomechanical properties ( < 0.05) and preserved the structural morphology of the interface after aging. Pretreatment of acid-etched dentine using specific flavonoid-containing solutions may be a promising approach to improve both the nanomechanical properties and the durability of modern universal adhesive systems.
本研究的目的是通过微拉伸粘结强度测试（μTBS）、纳米力学性能和超微形态共聚焦激光扫描显微镜（CLSM），评估几种实验性预处理交联剂溶液对使用代表性通用粘结系统形成的树脂-牙本质界面的影响。在酸蚀后，应用五种含有不同黄酮类化合物的实验溶液作为牙本质预处理。还设置了一个不含黄酮类化合物的对照预处理组。然后应用一种代表性的现代通用粘结剂，接着堆积3毫米厚的复合材料。将标本切成小条，并沿界面进行μTBS测试或纳米压痕分析（24小时或25000次热循环）。还使用CLSM评估聚合物-树脂界面的超微形态。结果采用双向方差分析和Bonferroni事后检验进行分析（α = 0.05）。所有黄酮类化合物均提高了短期和长期的μTBS值（P < 0.01），而只有一些特定的此类溶液改善了纳米力学性能（P < 0.05），并在老化后保持了界面的结构形态。使用特定的含黄酮类化合物溶液对酸蚀牙本质进行预处理可能是一种有前景的方法，可同时改善现代通用粘结系统的纳米力学性能和耐久性。
