Sahithi Durga, Nagarakanti Sreenivas, Prudhvi Sravya Sri, Gunupati Sumanth, Biradavolu Sukrutha, Chiruvella Bhagyasri, G Rishitha, Gudur Tejasri, Neravati Charitha
Department of Periodontology, Narayana Dental College and Hospital, Nellore, IND.
Cureus. 2025 Apr 14;17(4):e82268. doi: 10.7759/cureus.82268. eCollection 2025 Apr.
Background and aim Remarkable evidence supports the hypothesis that vitamin D influences and prevents the sequelae of periodontal disease. Its deficiency has also been found among patients with polycystic ovary syndrome (PCOS), and it could be attributed to the polymorphisms in the vitamin D receptor (VDR) gene. Hence, the goal of this study is to assess the periodontal health of PCOS participants and investigate the serum vitamin D levels in patients with PCOS and periodontitis. Methods and material A cross-sectional study was conducted on 100 female participants between the ages of 18 to 40 years and were equally divided into four groups: Group 1: participants with periodontitis only; Group 2: participants with PCOS only; Group 3: participants with periodontitis and PCOS; and Group 4: participants without periodontitis and PCOS. Results Serum vitamin D levels in Group 1 (35.40±3.862), Group 2 (31.20±5.888), Group 3 (32.12±3.811), and Group 4 (33.24±5.885) presented no statistically significant differences among the groups. Many people in all study groups had lower levels of serum vitamin D. In PCOS individuals, there is no discernible decline in periodontal health. Conclusions In this study, it was concluded that serum vitamin D levels do not significantly correlate with the prevalence of PCOS or periodontitis.
背景与目的 大量证据支持维生素D影响并预防牙周病后遗症这一假说。在多囊卵巢综合征(PCOS)患者中也发现了维生素D缺乏的情况,这可能归因于维生素D受体(VDR)基因的多态性。因此,本研究的目的是评估PCOS参与者的牙周健康状况,并调查PCOS合并牙周炎患者的血清维生素D水平。方法与材料 对100名年龄在18至40岁之间的女性参与者进行了一项横断面研究,她们被平均分为四组:第1组:仅患有牙周炎的参与者;第2组:仅患有PCOS的参与者;第3组:患有牙周炎和PCOS的参与者;第4组:未患有牙周炎和PCOS的参与者。结果 第1组(35.40±3.862)、第2组(31.20±5.888)、第3组(32.12±3.811)和第4组(33.24±5.885)的血清维生素D水平在各组之间无统计学显著差异。所有研究组中的许多人血清维生素D水平较低。在PCOS个体中,牙周健康没有明显下降。结论 在本研究中,得出的结论是血清维生素D水平与PCOS或牙周炎的患病率没有显著相关性。