Coelho Ana, Amaro Inês, Apolónio Ana, Paula Anabela, Saraiva José, Ferreira Manuel Marques, Marto Carlos Miguel, Carrilho Eunice
Faculty of Medicine, Institute of Integrated Clinical Practice, University of Coimbra, 3000-075 Coimbra, Portugal.
Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR), University of Coimbra, 3000-548 Coimbra, Portugal.
Int J Mol Sci. 2021 Apr 22;22(9):4398. doi: 10.3390/ijms22094398.
Some authors have been proposing the use of cavity disinfectants in order to reduce, or even eliminate, the effect of the microorganisms present in a dental cavity before a restoration is placed. The aim of this study was to evaluate the effect of different cavity disinfectants on bond strength and clinical success of composite and glass ionomer restorations on primary teeth. The research was conducted using Cochrane Library, PubMed/MEDLINE, SCOPUS, and Web of Science for articles published up to February 2021. The search was performed according to the PICO strategy. The evaluation of the methodological quality of each in vitro study was assessed using the CONSORT checklist for reporting in vitro studies on dental materials. Sixteen in vitro studies and one in situ study fulfilled the inclusion criteria and were analyzed. Chlorhexidine was the most studied cavity disinfectant, and its use does not compromise dentin bonding. Sodium hypochlorite is a promising alternative, but more research on its use is required to clearly state that it can safely be used as a cavity disinfectant for primary teeth. Although other disinfectants were studied, there is a low-level evidence attesting their effects on adhesion, therefore their use should be avoided.
一些作者一直提议使用窝洞消毒剂，以便在进行修复之前减少甚至消除存在于牙洞内的微生物的影响。本研究的目的是评估不同窝洞消毒剂对乳牙复合树脂和玻璃离子修复体的粘结强度及临床成功率的影响。该研究通过Cochrane图书馆、PubMed/MEDLINE、SCOPUS和Web of Science进行，检索截至2021年2月发表的文章。检索按照PICO策略进行。使用CONSORT清单对每项体外研究的方法学质量进行评估，该清单用于报告牙科材料的体外研究。16项体外研究和1项体内研究符合纳入标准并进行了分析。洗必泰是研究最多的窝洞消毒剂，其使用不会影响牙本质粘结。次氯酸钠是一种有前景的替代品，但需要更多关于其使用的研究，以明确说明它可以安全地用作乳牙的窝洞消毒剂。尽管对其他消毒剂进行了研究，但仅有低水平证据证明它们对粘结的影响，因此应避免使用。
