Wang Kangyu, Zhang Zixuan, Li Shaokun, Hu Jian, Liu Tao, Jiang Yang, Wu Jun, Lu Minghai, Zhao Mingzhu, Li Li, Zhu Lei, Wang Yanfang, Wang Yi, Zhang Meiping
College of Life Science, Jilin Agricultural University, Changchun 130118, China.
Jilin Engineering Research Center Ginseng Genetic Resources Development and Utilization, Changchun 130118, China.
Life (Basel). 2021 Apr 25;11(5):387. doi: 10.3390/life11050387.
C. A. Meyer is a kind of renascent herb that belongs to the genus in the family . It is a traditional Chinese precious herbal medicine with a long history of medicinal use. Ginsenoside Rb3 is one of the important active ingredients in ginseng and has important physiological activity in the treatment of many diseases. In this study, we screened and systematically analyzed the candidate genes related to ginsenoside Rb3 synthesis through bioinformatics methods; discussed the functions, expression patterns, and interactions of the genes related to ginsenoside Rb3 synthesis; and finally, selected seven genes, mainly that directly contribute to the synthesis of ginsenoside Rb3. This study provides a reference for revealing the expression rules of ginsenoside Rb3 synthesis-related genes and elucidating the regulatory mechanism of methyl jasmonate, lays a theoretical foundation for the research of ginsenoside Rb3 synthesis, and provides theoretical and technical support for the factory production of ginsenoside monomer saponins.
C.A. 迈耶是一种属于[具体科属信息缺失]科[具体属信息缺失]属的新生草本植物。它是一种具有悠久药用历史的中国传统珍贵草药。人参皂苷Rb3是人参中的重要活性成分之一,在多种疾病的治疗中具有重要的生理活性。在本研究中,我们通过生物信息学方法筛选并系统分析了与人参皂苷Rb3合成相关的候选基因;讨论了与人参皂苷Rb3合成相关基因的功能、表达模式及相互作用;最后,筛选出七个主要直接参与人参皂苷Rb3合成的基因。本研究为揭示人参皂苷Rb3合成相关基因的表达规律及阐明茉莉酸甲酯的调控机制提供了参考,为人参皂苷Rb3合成的研究奠定了理论基础,并为工厂化生产人参皂苷单体皂苷提供了理论和技术支持。