INSERM, University Limoges, CH Esquirol, IRD, U1094 Tropical Neuroepidemiology, Neurology, Limoges, France.
Pôle Universitaire de Psychiatrie de l'Adulte, de l'Agée et d'Addictologie, Centre Hospitalier Esquirol, 87000, Limoges, France.
BMC Psychiatry. 2021 May 1;21(1):223. doi: 10.1186/s12888-021-03228-9.
Assessment of cognitive disorders in schizophrenia is becoming a part of clinical and research practice by using batteries that differ widely in their content. The Brief Assessment of Cognition in Schizophrenia (BACS) was developed to cover the main cognitive deficits of schizophrenia. The objective of this study was to assess concurrent validity of the Arabic version of the BACS with a standard neurocognitive battery of tests in Lebanese patients with schizophrenia and healthy controls.
A sample of 120 stable inpatients diagnosed with schizophrenia and 60 healthy controls received the Arabic version of the BACS in a first session, and a standard battery in a second session.
Mean duration of completion for the BACS was 31.2 ± 5.4 min in patients with schizophrenia. All tests demonstrated significant differences between controls and patients (p < .01). Principal components analysis demonstrated that a one-factor solution best fits our dataset (64.8% of the variance). High Cronbach alpha was found (.85). The BACS composite scores were significantly correlated with the standard battery composite scores in patients (r = .73, p < .001) and healthy controls (r = .78, p < .001). Also, correlation analysis between the BACS sub-scores and the standard battery sub-scores showed significant results (p < .05).
Results showed that the Arabic version of the BACS demonstrated high ability to discriminate patients with schizophrenia from healthy controls and it is a useful tool for assessing cognition in patients with schizophrenia and could be used in clinical practice in Lebanon.
通过使用内容差异很大的测试组合,评估精神分裂症患者的认知障碍已成为临床和研究实践的一部分。Brief Assessment of Cognition in Schizophrenia(BACS)是为了评估精神分裂症的主要认知缺陷而开发的。本研究的目的是评估阿拉伯语版 BACS 与黎巴嫩精神分裂症患者和健康对照组的标准神经认知测试组合的同时效度。
一组 120 名稳定的住院精神分裂症患者和 60 名健康对照者在第一次就诊时接受了阿拉伯语版 BACS 测试,在第二次就诊时接受了标准的神经认知测试组合。
精神分裂症患者完成 BACS 的平均时间为 31.2±5.4 分钟。所有测试均显示对照组和患者之间存在显著差异(p<.01)。主成分分析表明,一个因素解决方案最适合我们的数据(64.8%的方差)。Cronbach α 值较高(.85)。BACS 综合评分与患者(r=.73,p<.001)和健康对照组(r=.78,p<.001)的标准电池综合评分显著相关。BACS 分项评分与标准电池分项评分之间的相关分析也显示出显著结果(p<.05)。
结果表明,阿拉伯语版 BACS 具有较高的能力,能够区分精神分裂症患者和健康对照组,是评估精神分裂症患者认知能力的有用工具,可在黎巴嫩的临床实践中使用。