Demil Endeshaw, Fentie Tsegaw, Vidal Gema, Jackson Wendi, Lane Jennifer, Mekonnen Sefinew Alemu, Smith Woutrina
Bahir Dar Animal Health Investigation and Diagnostic Laboratory, P.O. Box 70, Bahir Dar, Ethiopia.
College of Veterinary Medicine and Animal Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia.
Prev Vet Med. 2021 Apr 21;191:105363. doi: 10.1016/j.prevetmed.2021.105363.
Bovine viral diarrhea (BVD) is a disease that affects cattle and other ruminants worldwide and causes considerable economic losses. A cross-sectional study was carried out between December 2017 and July 2018 with the aim to estimate the prevalence of Bovine Viral Diarrhea virus (BVDV) antibodies and to identify potential risk factors associated with the occurrence of the disease in dairy cattle in peri-urban areas of Gondar city, Northwest Ethiopia. A total of 339 serum samples obtained from randomly selected dairy cattle aged 6 months and older were assayed using a BVDV antibody competitive-Enzyme Linked Immunosorbent Assay (c-ELISA) kit. Descriptive statistics were used to estimate antibody prevalence of BVDV at animal and herd-level and logistic regression was used to identify potential risk factors. The study findings showed that the animal-level antibody prevalence of BVDV in the study area was 26.84 % (95 % CI: 22.1 %-31.6 %) and the herd-level seroprevalence was 68.3 % (95 % CI: 56.2 %-80.4 %). Logistic regression model demonstrated that age >2 years (OR = 4.75, 95 % CI: 2.20-10.26), herd size >11 (OR = 7.28, 95 % CI: 2.50-21.22), and poor farm hygiene (OR = 3.69, 95 % CI: 1.94-7.02), are potential risk factors associated with BVDV infection (P < 0.05). However, sex, faecal consistency and housing system were not associated with BVDV serostatus. The animal- and herd-level seroprevalence reports in Northwest Ethiopia can serve as a baseline finding for future BVD epidemiological investigations and to inform future control programs in the study region.
牛病毒性腹泻（BVD）是一种影响全球牛和其他反刍动物的疾病，会造成相当大的经济损失。2017年12月至2018年7月进行了一项横断面研究，旨在估计牛病毒性腹泻病毒（BVDV）抗体的流行率，并确定埃塞俄比亚西北部贡德尔市周边地区奶牛中与该疾病发生相关的潜在风险因素。使用BVDV抗体竞争酶联免疫吸附测定（c-ELISA）试剂盒对从随机选择的6个月及以上的奶牛中获得的339份血清样本进行检测。描述性统计用于估计动物和畜群水平上BVDV的抗体流行率，逻辑回归用于识别潜在风险因素。研究结果表明，研究区域内BVDV在动物水平的抗体流行率为26.84%（95%置信区间：22.1%-31.6%），畜群水平的血清阳性率为68.3%（95%置信区间：56.2%-80.4%）。逻辑回归模型表明，年龄>2岁（比值比=4.75，95%置信区间：2.20-10.26）、畜群规模>11（比值比=7.28，95%置信区间：2.50-21.22）以及农场卫生条件差（比值比=3.69，95%置信区间：1.94-7.02）是与BVDV感染相关的潜在风险因素（P<0.05）。然而，性别、粪便稠度和饲养系统与BVDV血清状态无关。埃塞俄比亚西北部动物和畜群水平的血清阳性率报告可作为未来BVD流行病学调查的基线结果，并为研究区域未来的控制计划提供信息。
