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使用预训练的Transformer架构从临床记录中提取心绞痛症状。

Extracting Angina Symptoms from Clinical Notes Using Pre-Trained Transformer Architectures.

作者信息

Eisman Aaron S, Shah Nishant R, Eickhoff Carsten, Zerveas George, Chen Elizabeth S, Wu Wen-Chih, Sarkar Indra Neil

机构信息

Center for Biomedical Informatics, Brown University, Providence RI.

The Warren Alpert Medical School, Brown University, Providence, RI.

出版信息

AMIA Annu Symp Proc. 2021 Jan 25;2020:412-421. eCollection 2020.

Abstract

Anginal symptoms can connote increased cardiac risk and a need for change in cardiovascular management. In this study, a pre-trained transformer architecture was used to automatically detect and characterize anginal symptoms from within the history of present illness sections of 459 primary care physician notes. Consecutive patients referred for cardiac testing were included. Notes were annotated for positive and negative mentions of chest pain and shortness of breath characterization. The results demonstrate high sensitivity and specificity for the detection of chest pain or discomfort, substernal chest pain, shortness of breath, and dyspnea on exertion. Model performance extracting factors related to provocation and palliation of chest pain were limited by small sample size. Overall, this study shows that pre-trained transformer architectures have promise in automating the extraction of anginal symptoms from clinical texts.

摘要

心绞痛症状可能意味着心脏风险增加以及需要改变心血管管理。在本研究中,使用了预训练的Transformer架构来自动从459份初级保健医生记录的现病史部分中检测和表征心绞痛症状。纳入了连续接受心脏检查的患者。对记录中关于胸痛和呼吸急促特征的阳性和阴性提及进行了注释。结果表明,该方法在检测胸痛或不适、胸骨后胸痛、呼吸急促和劳力性呼吸困难方面具有较高的敏感性和特异性。提取与胸痛激发和缓解相关因素的模型性能受到样本量小的限制。总体而言,本研究表明,预训练的Transformer架构在从临床文本中自动提取心绞痛症状方面具有前景。

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