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处理开放性骨折中的骨质流失

Managing bone loss in open fractures.

作者信息

Adamczyk Andrew, Meulenkamp Bradley, Wilken Geoffrey, Papp Steven

机构信息

The Ottawa Hospital, Division of Orthopaedics, University of Ottawa, Ottawa, Ontario, Canada.

出版信息

OTA Int. 2020 Mar 23;3(1):e059. doi: 10.1097/OI9.0000000000000059. eCollection 2020 Mar.

DOI:10.1097/OI9.0000000000000059
PMID:33937684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8081484/
Abstract

Segmental bone loss continues to pose substantial clinical and technical challenges to orthopaedic surgeons. While several surgical options exist for the treatment of these complex patients, there is not a clear consensus or specific guidelines on the optimal management of these injuries as a whole. Many factors must be taken into consideration when planning surgery for these individuals. In order for these techniques to yield optimal results, each injury must be approached in a step-wise and multidisciplinary fashion to ensure that care is taken in bone and wound bed preparation, that soft tissues are healthy and free of contaminants, and that the patient's medical condition has been optimized. Through this article, we will answer relevant questions and discuss common obstacles and challenges encountered with these complex injuries. We will also review the many treatment options available or in development to address this problem.

摘要

节段性骨缺损仍然给骨科医生带来重大的临床和技术挑战。虽然有几种手术选择可用于治疗这些复杂的患者,但对于如何整体优化处理这些损伤,目前尚无明确的共识或具体指南。为这些患者规划手术时必须考虑许多因素。为了使这些技术取得最佳效果,必须以逐步和多学科的方式处理每一处损伤,以确保在骨和创面准备过程中谨慎操作,确保软组织健康且无污染,并确保患者的身体状况已得到优化。通过本文,我们将回答相关问题,并讨论这些复杂损伤所遇到的常见障碍和挑战。我们还将回顾现有的或正在研发的许多治疗方案,以解决这一问题。

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本文引用的文献

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Injury. 2021 Oct;52(10):2926-2934. doi: 10.1016/j.injury.2019.08.013. Epub 2019 Aug 14.
2
Bone Repair Using the Masquelet Technique.采用Masquelet技术进行骨修复。
J Bone Joint Surg Am. 2019 Jun 5;101(11):1024-1036. doi: 10.2106/JBJS.18.00842.
3
Three-dimensional Bioprinting for Bone and Cartilage Restoration in Orthopaedic Surgery.三维生物打印在骨科手术中骨和软骨修复的应用。
通过制造人为畸形作为挽救伴有巨大胫骨和软组织缺损患者肢体的方法:26例报告
Strategies Trauma Limb Reconstr. 2023 Sep-Dec;18(3):133-139. doi: 10.5005/jp-journals-10080-1599.
4
Tibial lengthening for massive distal femoral bone loss.胫骨延长术治疗股骨远端大骨量丢失。
BMJ Case Rep. 2023 Nov 14;16(11):e254863. doi: 10.1136/bcr-2023-254863.
5
Current concepts of bone grafting in trauma surgery.创伤外科中骨移植的当前概念。
J Clin Orthop Trauma. 2023 Aug 5;43:102231. doi: 10.1016/j.jcot.2023.102231. eCollection 2023 Aug.
6
Retrograde calcaneo-talo-tibial nail, subtalar arthrodesis and fibula transposition in the treatment of traumatic bone and articulatory defect of the distal tibia and talocrural joint: A case report.逆行跟骨-距骨-胫骨钉、距下关节融合术及腓骨移位术治疗胫骨远端及踝关节创伤性骨与关节缺损:1例报告
Trauma Case Rep. 2022 Nov 24;42:100734. doi: 10.1016/j.tcr.2022.100734. eCollection 2022 Dec.
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Current Perspectives on the Management of Bone Fragments in Open Tibial Fractures: New Developments and Future Directions.开放性胫骨骨折中骨碎片处理的当前观点:新进展与未来方向
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Ann Med Surg (Lond). 2021 Nov 2;71:103020. doi: 10.1016/j.amsu.2021.103020. eCollection 2021 Nov.
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J Am Acad Orthop Surg. 2018 Nov 15;26(22):e477-e482. doi: 10.5435/JAAOS-D-17-00487.
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