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葡萄酒色斑治疗进展:综述。

Treatment Update of Port-Wine Stain: A Narrative Review.

出版信息

J Drugs Dermatol. 2021 May 1;20(5):515-518. doi: 10.36849/JDD.5005.

DOI:10.36849/JDD.5005
PMID:33938700
Abstract

Port-wine stain (PWS) is a congenital vascular malformation affecting 0.3–0.5% of normal population. These characteristic lesions arise due to the interplay of vascular, neural, and genetic factors. Treatment options include lasers, cosmetic tattooing, electrotherapy, cryosurgery, derma-abrasion, and skin grafting; however, none of these treatment alternatives appears to be satisfactory and is unable to provide consistent, satisfactory responses or even complete cures. Currently, laser is the treatment of choice, as it is comparatively safe and more effective than other procedures. The most commonly used modality is pulsed dye laser (PDL). The literature research includes peer-reviewed articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) to January 2020 and reference lists of respective articles. Only articles published in English language were included. J Drugs Dermatol. 20(5): doi:10.36849/JDD.5005.

摘要

葡萄酒色斑(PWS)是一种影响 0.3%–0.5%正常人群的先天性血管畸形。这些特征性病变是由于血管、神经和遗传因素的相互作用而产生的。治疗选择包括激光、美容纹身、电疗、冷冻疗法、皮肤磨蚀和植皮;然而,这些治疗选择似乎都不能令人满意,无法提供一致、满意的反应,甚至无法完全治愈。目前,激光是首选治疗方法,因为它相对安全,比其他手术更有效。最常用的方法是脉冲染料激光(PDL)。文献研究包括同行评议的文章(临床试验或科学综述)。通过搜索电子数据库(MEDLINE 和 PubMed),对截至 2020 年 1 月的文献进行了研究,并查阅了各自文章的参考文献列表。仅纳入了以英文发表的文章。J Drugs Dermatol. 20(5): doi:10.36849/JDD.5005.

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Treatment Update of Port-Wine Stain: A Narrative Review.葡萄酒色斑治疗进展:综述。
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Postepy Dermatol Alergol. 2025 Jun 13;42(3):313-319. doi: 10.5114/ada.2025.152120. eCollection 2025 Jun.
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Laser and light-based treatments for port-wine birthmarks - a systematic review and network meta-analysis.激光和光基疗法治疗葡萄酒色斑——一项系统评价和网状Meta分析
J Dtsch Dermatol Ges. 2025 Mar;23(3):293-301. doi: 10.1111/ddg.15612. Epub 2024 Dec 12.
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Vascular Malformations.血管畸形
Indian Dermatol Online J. 2024 Apr 23;15(3):415-430. doi: 10.4103/idoj.idoj_633_23. eCollection 2024 May-Jun.
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Clinical Observation on the Therapeutic Effect of Port-Wine Stains with Intravenous Injection of Hematoporphyrin Monomethyl Ether (HMME).静脉注射血卟啉单甲醚(HMME)治疗鲜红斑痣的临床疗效观察
Clin Cosmet Investig Dermatol. 2024 May 21;17:1183-1191. doi: 10.2147/CCID.S459613. eCollection 2024.
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The Long-Pulse Potassium-Titanyl-Phosphate Laser: Promising Treatment for Resistant Port-Wine Stains.长脉冲磷酸钛氧钾激光:治疗难治性葡萄酒色斑的有前景疗法。
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