College of Food Science & Engineering, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, China; Key Laboratory of Resource Biology and Biotechnology in Western China, College of Life Science, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, China.
Key Laboratory of Resource Biology and Biotechnology in Western China, College of Life Science, Northwest University, No. 229 Taibai North Road, Xi'an, Shaanxi 710069, China.
Food Chem. 2021 Oct 1;358:129883. doi: 10.1016/j.foodchem.2021.129883. Epub 2021 Apr 20.
Lentinus edodes, an important edible mushroom cultivated in East Asia for thousands of years, has been widely used as food and medicinal ingredient worldwide. Modern phytochemistry studies have demonstrated that L. edodes is very rich in bioactive polysaccharides, especially the β-glucans. Over the past two decades, the isolation, chemical properties, and bioactivities of polysaccharides from fruiting bodies, mycelium and fermentation broth of L. edodes have been drawing much attention from scholars around the world. It has been demonstrated that L. edodes polysaccharides possess various remarkable biological activities, including anti-oxidant, anti-tumor, anti-aging, anti-inflammation, immunomodulatory, antiviral, and hepatoprotection effects. This review summarizes the recent development of polysaccharides from L. edodes including the isolation methods, structural features, bioactivities and mechanisms, and their structure-activity relationship, which can provide useful research underpinnings and update information for their further application as therapeutic agents and functional foods.
香菇，一种在东亚地区被广泛栽培了数千年的重要食用蘑菇，在全球范围内已被广泛用作食品和药用成分。现代植物化学研究表明，香菇富含生物活性多糖，尤其是β-葡聚糖。在过去的二十年中，从香菇子实体、菌丝体和发酵液中分离多糖的化学性质和生物活性引起了世界各地学者的关注。研究表明，香菇多糖具有多种显著的生物活性，包括抗氧化、抗肿瘤、抗衰老、抗炎、免疫调节、抗病毒和保肝作用。本文综述了近年来香菇多糖的研究进展，包括分离方法、结构特征、生物活性和作用机制及其构效关系，为其作为治疗剂和功能性食品的进一步应用提供了有用的研究基础和最新信息。
