Apel I, Jacobs E, Kist M, Bredt W
Abteilung Mikrobiologie und Hygiene, Klinikum der Universität Freiburg.
Zentralbl Bakteriol Mikrobiol Hyg A. 1988 Apr;268(2):271-6. doi: 10.1016/s0176-6724(88)80012-9.
Campylobacter pylori strains were isolated and serum samples were obtained from 63 patients. Immunoblots of 52 patients sera using their own isolates as antigen showed a 120 kDa band, which was missing in the other 11 isolates and the respective sera. This band was not detected in other Campylobacter species. Effects of trypsin treatment of bacteria and absorption of sera by live organisms suggest a C. pylori-specific surface protein.
从63名患者中分离出幽门螺杆菌菌株并采集血清样本。用患者自身分离菌株作为抗原对52名患者的血清进行免疫印迹分析，结果显示有一条120 kDa的条带，而在其他11株分离菌株及相应血清中未出现该条带。在其他弯曲杆菌属物种中未检测到这条带。对细菌进行胰蛋白酶处理以及用活生物体吸收血清的实验结果表明这是一种幽门螺杆菌特异性表面蛋白。
