• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

在炎症与血栓之间：COVID-19 中的血管内皮细胞。

Between inflammation and thrombosis: endothelial cells in COVID-19.

机构信息

Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria.

Authors contributed equally.

出版信息

Eur Respir J. 2021 Sep 9;58(3). doi: 10.1183/13993003.00377-2021. Print 2021 Sep.

DOI:10.1183/13993003.00377-2021
PMID:33958433
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8112008/
Abstract

https://bit.ly/3eQObIR

摘要

链接

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a843/8112008/d5fcae663367/ERJ-00377-2021.01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a843/8112008/d5fcae663367/ERJ-00377-2021.01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a843/8112008/d5fcae663367/ERJ-00377-2021.01.jpg

相似文献

1
Between inflammation and thrombosis: endothelial cells in COVID-19.在炎症与血栓之间：COVID-19 中的血管内皮细胞。
Eur Respir J. 2021 Sep 9;58(3). doi: 10.1183/13993003.00377-2021. Print 2021 Sep.
2
Recombinant ACE2 Expression Is Required for SARS-CoV-2 To Infect Primary Human Endothelial Cells and Induce Inflammatory and Procoagulative Responses.重组 ACE2 表达是 SARS-CoV-2 感染原代人血管内皮细胞并诱导炎症和促凝反应所必需的。
mBio. 2020 Dec 11;11(6):e03185-20. doi: 10.1128/mBio.03185-20.
3
IL-1 induces throboxane-A2 (TxA2) in COVID-19 causing inflammation and micro-thrombi: inhibitory effect of the IL-1 receptor antagonist (IL-1Ra).白细胞介素-1（IL-1）在 COVID-19 中诱导血栓烷 A2（TxA2）的产生，导致炎症和微血栓形成：白细胞介素-1 受体拮抗剂（IL-1Ra）的抑制作用。
J Biol Regul Homeost Agents. 2020;34(5):1623-1627. doi: 10.23812/20-34-4EDIT-65.
4
Monoclonal antibody therapy in COVID-19.COVID-19 中的单克隆抗体疗法。
J Biol Regul Homeost Agents. 2021 Mar-Apr;35(2):423-427. doi: 10.23812/Conti_Edit_35_2_1.
5
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets.新型冠状病毒病病理生理学中的炎症与血栓形成：蛋白水解酶激活和嘌呤能受体作为驱动因素和候选治疗靶点。
Physiol Rev. 2021 Apr 1;101(2):545-567. doi: 10.1152/physrev.00035.2020. Epub 2020 Oct 30.
6
COVID-19 - Endothelial Axis and Coronary Artery Bypass Graft Patency: a Target for Therapeutic Intervention?新冠病毒-内皮轴与冠状动脉搭桥术通畅性：治疗干预靶点？
Braz J Cardiovasc Surg. 2020 Oct 1;35(5):757-763. doi: 10.21470/1678-9741-2020-0303.
7
[SARS-CoV-2 infection as a thrombo-inflammatory endothelial disease].[新型冠状病毒肺炎作为一种血栓性炎症性内皮疾病]
Rev Med Chil. 2020 Oct;148(10):1467-1474. doi: 10.4067/S0034-98872020001001467.
8
Acute peripheral arterial thrombosis in COVID-19. Role of endothelial inflammation.新型冠状病毒肺炎中的急性外周动脉血栓形成。内皮炎症的作用。
Br J Surg. 2020 Sep;107(10):e444-e445. doi: 10.1002/bjs.11904. Epub 2020 Aug 5.
9
[Endothelial dysfunction in COVID- 19 and cognitive impairment].[新型冠状病毒肺炎中的内皮功能障碍与认知障碍]
Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(6):93-99. doi: 10.17116/jnevro202112106193.
10
Mast cells activated by SARS-CoV-2 release histamine which increases IL-1 levels causing cytokine storm and inflammatory reaction in COVID-19.SARS-CoV-2 激活的肥大细胞释放组织胺，增加白细胞介素-1 水平，导致 COVID-19 中的细胞因子风暴和炎症反应。
J Biol Regul Homeost Agents. 2020;34(5):1629-1632. doi: 10.23812/20-2EDIT.

引用本文的文献

1
Long-term in-hospital mortality and chronic thromboembolic pulmonary hypertension after COVID-19-associated pulmonary embolism in France: a nationwide study.法国新冠病毒相关肺栓塞后长期住院死亡率和慢性血栓栓塞性肺动脉高压：一项全国性研究
ERJ Open Res. 2025 Sep 15;11(5). doi: 10.1183/23120541.01387-2024. eCollection 2025 Sep.
2
Serum sICAM-1 and Galectin-3 Levels in Diabetic Patients with COVID-19.2019冠状病毒病糖尿病患者的血清可溶性细胞间黏附分子-1和半乳糖凝集素-3水平
Viruses. 2025 Jul 17;17(7):1005. doi: 10.3390/v17071005.
3
CXCL10-dependent epithelial-vascular cross-talk for endothelial activation following SARS-CoV-2 infection.

本文引用的文献

1
Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19.内皮功能障碍和免疫血栓形成是 COVID-19 的关键发病机制。
Nat Rev Immunol. 2021 May;21(5):319-329. doi: 10.1038/s41577-021-00536-9. Epub 2021 Apr 6.
2
Scoring cytokine storm by the levels of MCP-3 and IL-8 accurately distinguished COVID-19 patients with high mortality.通过MCP-3和IL-8水平对细胞因子风暴进行评分，能够准确区分出死亡率高的新冠肺炎患者。
Signal Transduct Target Ther. 2020 Dec 14;5(1):292. doi: 10.1038/s41392-020-00433-y.
3
Plasma mediators in patients with severe COVID-19 cause lung endothelial barrier failure.
SARS-CoV-2感染后CXCL10依赖性上皮-血管相互作用促进内皮细胞活化
Sci Rep. 2025 Jul 1;15(1):21129. doi: 10.1038/s41598-025-08329-z.
4
The Molecular Mechanisms of Cognitive Dysfunction in Long COVID: A Narrative Review.长新冠认知功能障碍的分子机制：一项叙述性综述
Int J Mol Sci. 2025 May 26;26(11):5102. doi: 10.3390/ijms26115102.
5
Transcriptional signatures of endothelial cells shape immune responses in cardiopulmonary health and disease.内皮细胞的转录特征塑造心肺健康与疾病中的免疫反应。
JCI Insight. 2025 May 22;10(10). doi: 10.1172/jci.insight.191059.
6
An analysis of novel endothelial biomarkers to ascertain their role as prognostic indicators in severe COVID-19 illness.分析新型内皮生物标志物，以确定它们在重症COVID-19疾病中作为预后指标的作用。
Indian J Med Res. 2025 Mar;161(3):298-305. doi: 10.25259/IJMR_915_2024.
7
Diagnostic biomarkers and immune infiltration profiles common to COVID-19, acute myocardial infarction and acute ischaemic stroke using bioinformatics methods and machine learning.使用生物信息学方法和机器学习确定2019冠状病毒病、急性心肌梗死和急性缺血性中风共有的诊断生物标志物和免疫浸润特征
BMC Neurol. 2025 May 8;25(1):201. doi: 10.1186/s12883-025-04212-6.
8
A Systematic Review of Endothelial Dysfunction in Chronic Venous Disease-Inflammation, Oxidative Stress, and Shear Stress.慢性静脉疾病中内皮功能障碍的系统评价——炎症、氧化应激和剪切应力
Int J Mol Sci. 2025 Apr 12;26(8):3660. doi: 10.3390/ijms26083660.
9
Impact of SARS-CoV-2 Wuhan and Omicron Variant Proteins on Type I Interferon Response.严重急性呼吸综合征冠状病毒2型武汉株和奥密克戎变异株蛋白对I型干扰素反应的影响。
Viruses. 2025 Apr 15;17(4):569. doi: 10.3390/v17040569.
10
Heme Oxygenase-1 Modulates Macrophage Polarization Through Endothelial Exosomal miR-184-3p and Reduces Sepsis-Induce Lung Injury.血红素加氧酶-1通过内皮细胞外泌体miR-184-3p调节巨噬细胞极化并减轻脓毒症诱导的肺损伤。
Int J Nanomedicine. 2025 Apr 18;20:5039-5057. doi: 10.2147/IJN.S506830. eCollection 2025.
严重 COVID-19 患者的血浆介质导致肺血管内皮屏障功能衰竭。
Eur Respir J. 2021 Mar 11;57(3). doi: 10.1183/13993003.02384-2020. Print 2021 Mar.
4
COVID-19 is, in the end, an endothelial disease.COVID-19 归根结底是一种血管内皮疾病。
Eur Heart J. 2020 Sep 1;41(32):3038-3044. doi: 10.1093/eurheartj/ehaa623.
5
Injury to the Endothelial Glycocalyx in Critically Ill Patients with COVID-19.新型冠状病毒肺炎重症患者的内皮糖萼损伤
Am J Respir Crit Care Med. 2020 Oct 15;202(8):1178-1181. doi: 10.1164/rccm.202007-2676LE.
6
Von Willebrand factor (vWF): marker of endothelial damage and thrombotic risk in COVID-19?血管性血友病因子（vWF）：COVID-19 中内皮损伤和血栓形成风险的标志物？
Clin Med (Lond). 2020 Sep;20(5):e178-e182. doi: 10.7861/clinmed.2020-0346. Epub 2020 Jul 21.
7
Endotheliopathy in COVID-19-associated coagulopathy: evidence from a single-centre, cross-sectional study.新型冠状病毒肺炎相关凝血病中的内皮病变：来自一项单中心横断面研究的证据
Lancet Haematol. 2020 Aug;7(8):e575-e582. doi: 10.1016/S2352-3026(20)30216-7. Epub 2020 Jun 30.
8
Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19.新型冠状病毒肺炎的肺血管内皮细胞炎症、血栓形成和血管生成。
N Engl J Med. 2020 Jul 9;383(2):120-128. doi: 10.1056/NEJMoa2015432. Epub 2020 May 21.
9
Confirmation of the high cumulative incidence of thrombotic complications in critically ill ICU patients with COVID-19: An updated analysis.确认 COVID-19 重症 ICU 患者的血栓并发症累积发生率较高：更新分析。
Thromb Res. 2020 Jul;191:148-150. doi: 10.1016/j.thromres.2020.04.041. Epub 2020 Apr 30.
10
Endothelial cell infection and endotheliitis in COVID-19.新型冠状病毒肺炎中的内皮细胞感染与内皮炎
Lancet. 2020 May 2;395(10234):1417-1418. doi: 10.1016/S0140-6736(20)30937-5. Epub 2020 Apr 21.