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采用联合经肝内和经肝外入路治疗医源性肝内胆管损伤的长期疗效。

Long-term outcomes in the repair of intrahepatic iatrogenic bile duct lesions using a combined intraglissonian and extraglissonian approach.

机构信息

Department of Surgery. HBP Unit, Virgen de la Arrixaca University Hospital, IMIB-Arrixaca, Murcia, Spain.

出版信息

Langenbecks Arch Surg. 2022 Feb;407(1):403-408. doi: 10.1007/s00423-021-02188-8. Epub 2021 May 8.

Abstract

PURSPOSE

Iatrogenic bile duct injuries (IBDI) with intrahepatic involvement are a serious and challenging surgical complication that can have disastrous consequences in terms of morbidity and mortality.

METHODS

We collected the patients with IBDI type (E4) between January 1991 and March 2020 in our hospital. The objective of the study was to present the long-term results of a extraglissonian approach and intraglissonian biliary reconstruction in a series of patients with intrahepatic bile duct injuries after cholecystectomy. We also detail our preoperative management and the standardization of the technique.

RESULTS

An extraglissonian approach with partial hepatic resection of the base of segments 4b and 5 and intraglissonian Roux-en-Y hepaticojejunostomy for biliary reconstruction using to several branches was performed in 10 patients with E4 Strassberg type intrahepatic lesions. Only one patient had postoperative bile leak (Clavien 3a). Surgical time was 260 min (IQR, 210-490). We left transanastomotic catheter (between 2 and 5) in situ for 3 and 6 months after surgery. The patients remained asymptomatic over a median follow-up of 169 months (IQR 129-234).

CONCLUSION

This biliary reconstruction technique obtains positive long-term outcomes in patients with severe intrahepatic lesions.

摘要

目的

伴有肝内累及的医源性胆管损伤(IBDI)是一种严重且具有挑战性的手术并发症,在发病率和死亡率方面可能产生灾难性的后果。

方法

我们收集了 1991 年 1 月至 2020 年 3 月期间我院 E4 型 IBDI 患者的资料。本研究的目的是展示一系列胆囊切除术后肝内胆管损伤患者采用非 Glisson 入路和 Glisson 内胆管重建的长期结果。我们还详细介绍了我们的术前管理和技术标准化。

结果

10 例 E4 型 Strasberg 肝内病变患者采用非 Glisson 入路,行部分肝切除 4b 和 5 段底部,Glisson 内 Roux-en-Y 肝肠吻合术用于重建多条胆管分支。只有 1 例患者术后出现胆漏(Clavien 3a 级)。手术时间为 260 分钟(IQR,210-490)。术后我们将经吻合口的导管(2-5 根)原位保留 3-6 个月。中位随访 169 个月(IQR,129-234)期间,患者均无症状。

结论

对于严重肝内病变患者,这种胆管重建技术可获得良好的长期效果。

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